BSc, MSc, PhD
- Primary position:
- Director of Enterprise
- Other positions:
- Chair in Neuroscience, Principal Investigator (Neuropharmacology & physiology)
Professor of Neuroscience. University of Southampton, UK.
Reader. School of Biological Sciences, University of Southampton, UK.
Post-doctoral Research Fellow. Department of Neurophysiology, University of Southampton, UK.
PhD Neuropharmacology. University of Southampton, UK.
MSc Biochemical Pharmacology. University of Southampton, UK.
BSc Physiology. University College, Cardiff, UK.
The University of Southampton's electronic library (e-prints)
Conference or Workshop Item
Holden-Dye L and Walker RJ. Anthelmintic Drugs. (2007) WormBook, ed. The C. elegans Research Community, WormBook, doi/10.1895/wormbook. http://www.wormbook.org.
Franks CJ, Holden-Dye L, Bull K, Luedtke S, Walker RJ. (2006) Anatomy, physiology and pharmacology of Caenorhabditis elegans pharynx: a model to define gene function in a simple neural system. Invert Neurosci. 6:105-22
I am interested in the fundamental processes of neuronal communication and have established research expertise in simple invertebrate preparations. Much of my work now resonates with issues concerning mental health such as addiction and neurodegeneration. My expertise in invertebrate neuroscience, and in particular nematode neural systems and C. elegans, positions me well to participate in drug discovery and mode of action programmes for novel antiparasitics. For the last decade I have collaborated with industry to improve prospects for parasitic nematode control. The experimental approaches deployed in my research encompass genetics through to whole animal physiology and incorporate novel methods for tracking animal behaviour and signal processing.
Primary research group: Biomedical Sciences
Given the significant sequence similarity between members of the GTG/GPHR family, we are testing whether the GTG/GPHR family has a conserved physiological function in diverse organisms.
Characterisation of cue-dependent behaviour in plant parasitic nematodes: the neurobiology of host plant invasion
The neurobiology of plant parasitic nematodes.
Changes in the pattern of behavior with increasing alcohol intake in humans reflect its complex effects on the brain.
BIOL1011 Foundations of Physiology I
BIOL1013 Cell Communications Foundations of Physiology
BIOL2016 Pharmacology A
BIOL2017 Pharmacology B
BIOL3021 Cellular and Molecular Neuroscience
BIOL3027 Selective toxicity
BIOL3018 Molecular Pharmacology
BIOL3020 Systems Neuroscience
BIOL3025 Neuropharmacology of CNS Disorders
Contributions to postgraduate teaching programme
Other teaching related responsibilities
Neuroscience tutorials for second year
Contribution to two modules at Winchester School of Art, one in fashion design and the other in graphic arts by providing briefs for neuroscience inspired projects (2 launches in this academic year).
Contribution to Faculty of Medicine, Scientific Basis of Medicine module (Alcohol)
Professor Lindy Holden-Dye
FNES Student Office
Centre for Biological Sciences
Faculty of Natural & Environmental Sciences
Life Sciences Building 85
University of Southampton
Room Number: 85/3051