The University of Southampton
Courses

HPRS2024 Respiratory & Sleep Physiology

Module Overview

Aims and Objectives

Module Aims

To ensure that the student understands the breadth of the application of science within Respiratory and Sleep Sciences and building on previous learning develops and applies knowledge and understanding in Respiratory and Sleep Sciences.

Learning Outcomes

Knowledge and Understanding

Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:

  • Describe the meaning of the abbreviations and units used in Respiratory and Sleep Science.
  • Explain the principles of operation of respiratory gas analysers to measure commonly used gases in Respiratory measurement.
  • Explain the routine procedures for care and calibration of gas analysers.
  • Explain the structure-function relationship determining gas exchange and Carbon Monoxide (CO) Transfer Factor.
  • Explain the principles and operation of pulse oximeters.
  • Explain the principles, concepts and basic operation of continuous positive airway pressure (CPAP) equipment and modalities.
  • Recognise the need for effective communication skills and respect for the rights, dignity and privacy of patients.
  • Recognise the implications of working in multidisciplinary teams with regard to communiation, safety and patient care.
  • Become informed recipients of research evidence in healthcare science by critically appraising professional journals and associated literature using established appraisal tools.
  • Explain the concept of “normal” and the calculation and use of normal ranges.
  • Discuss normal physiological variability in humans.
  • Describe the generation and use of reference ranges to define normal and abnormal lung function.
  • Discuss the terms calibration and quality assurance and explain their use for all measurements undertaken in Respiratory and Sleep Science.
  • Explain the application of dynamic lung volumes and flows in routine clinical practice.
  • Explain the methods that can be used to estimate static lung volumes.
  • Compare different techniques to estimate lung volumes and know the limitations of each technique.
  • Discuss the role of inhaled drug therapy in the management of respiratory disease.
Subject Specific Intellectual and Research Skills

Having successfully completed this module you will be able to:

  • Discuss complex scientific information in ways that can be understood by patients and practitioners in other areas.
  • Use correct terminology when discussing scientific issues
  • Work safely in radiation areas.

Syllabus

In this module students will build on Year 1 learning and begin detailed learning that underpins the routine practical techniques. Pathophysiological changes that occur with common lung diseases including: • Chronic Obstructive Pulmonary Disease • Asthma • Restrictive Lung Disease • Pulmonary Vascular Disease • Congenital and genetic Lung Conditions • Respiratory Muscle Disorders • Occupational Lung Disease • Lung Cancer • Cystic Fibrosis • Obstructive Sleep Apnoea The role of respiratory mechanics in control of breathing Effect of neuromuscular disease on the respiratory system Assessment of Lung Function • Techniques used in the assessment of lung function • Reference ranges o Uses o Limitations • Reporting Systems • Static Lung Volumes o Characteristics of recording equipment o Indications o Contra-Indications o Recommended measurement technique o Calculations o Cleaning Procedures o Common problems o Normal values and interpretation of results • Dynamic Lung Volumes and Flow o Characteristics of recording equipment o Indications o Contra-Indications o Recommended measurement technique o Calculations o Cleaning Procedures o Common problems o Normal values and interpretation of results • Reversibility Testing o Characteristics of recording equipment o Indications o Contra-Indications o Recommended measurement technique o Calculations o Common problems o Normal values and interpretation of results • Measurement of Gas Transfer o Characteristics of recording equipment o Indications o Contra-Indications o Recommended measurement technique o Calculations o Cleaning Procedures o Common problems o Normal values and interpretation of results • Spot Check Pulse Oximetry o Characteristics of recording equipment o Indications o Contra-Indications o Recommended measurement technique o Common problems o Normal values and interpretation of results • Overnight Pulse Oximetry o Characteristics of recording equipment o Indications o Contra-Indications o Recommended measurement technique o Common problems o Normal values • CPAP Machines o Function/ types / modalities o Cleaning & filter changing o Mask/interface types o Contraindications o Side effects/troubleshooting o Patient education • Respiratory muscle Assessment o Mouth pressures o Sniff pressures o Supine and sitting vital capacity (VC)

Special Features

This module will be supported by the very strong science base within the University of Southampton. We have very successful programmes in life sciences, medicine, engineering and science (including the Institute of Sound & Vibration Research) all of which are well resourced in both staff and equipment. It is our intention to maximise opportunities for our students to work within this robust academic environment by sharing learning opportunities and being exposed to experts in the field. Students will have access to state of the art laboratories both on Highfield campus and at the Southampton General Hospital which are fully equipped with learning resources. The human morphology laboratory, for instance, will provide a strong learning environment for our students as they are introduced to anatomy and physiology. In order to support this programme the Faculty is investing in four new ‘Lab-Tutor’ simulated learning software packages with the associated hardware. These will supplement the existing simulated learning equipment (SimMan) which have been used very successfully on our existing programmes.

Learning and Teaching

Teaching and learning methods

Students will learn by exploring material in seminars and laboratory practical’s, in conjunction with directed learning. Students will be encouraged to take responsibility for the development of their own learning by utilising a variety of means such as multimedia resources, and the library, and by self-directed development of the study skills necessary to access these resources.

TypeHours
Wider reading or practice45
Tutorial12
Preparation for scheduled sessions90
Lecture100
Follow-up work45
Completion of assessment task26
Revision25
Practical classes and workshops32
Total study time375

Resources & Reading list

Terry Des Jardins, George G. Burton (2010). Clinical Manifestations and Assessment of Respiratory Disease. 

Mechanical ventilation (2009). Mechanical ventilation. 

Author: Clete A. Kushida, Editor: Clete A. Kushida (2008). Handbook of Sleep Disorders. 

Authors: W. T. McNicholas, Eliot A. Phillipson, Editors: W. T. McNicholas, Eliot A. Phillipson (2002). Breathing disorders in sleep. 

John Burnard West (2008). Pulmonary pathophysiology: the essentials. 

Assessment

Summative

MethodPercentage contribution
Exam  (2 hours) 50%
Written essay  (2000 words) 50%

Repeat Information

Repeat type: Internal & External

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