Translational Medicine

Learning Outcomes

Transferable and Generic Skills

Having successfully completed this module you will be able to:

• Develop relationships to enable effective interdisciplinary work
• Engage in self-directed and reflective learning
• Engage in self-directed and reflective learning
• Deal with complex clinical and scientific issues both systematically and creatively
• Develop skills relating to lifelong professional learning
• Plan and implement tasks at a professional level
• Develop oral presentation skills
• Develop good communication skills (written, listening and verbal).

Knowledge and Understanding

Having successfully completed this module, you will be able to demonstrate knowledge and understanding of:

• Analysing the results of clinical studies using appropriate statistical tests
• Developing solutions to complex clinical problems with a specific emphasis on patient impacts
• Evaluating the range of clinical study designs available for assessment of novel devices, processes or software solutions
• The key regulatory bodies involved in oversight and conduct of pre-clinical and clinical research studies, the key legislation underpinning these bodies and the roles and responsibilities of each organisation
• Appraising the quality of clinical studies to differentiate between ethically run, well designed clinical studies and those that are not
• The pathways for obtaining funding for clinical trials and routes to commercialisation of new technologies, including an appreciation of the technology life cycle
• Designing a clinical study that takes into account all ethical, legal and practical considerations
• Planning the primary outcomes of a clinical study to obtain a clear result and be able to differentiate between these primary outcomes and more secondary or exploratory outcomes

Postgraduate study skills:

Information for writing assignments: Scientific and IT skills for report writing, How to read a scientific paper / Critical appraisal, Academic Integrity, Managing references (searching, storing, citing)

Clinical study conduct

NIHR-accredited Good Clinical Practice (GCP) training

Research Design

Pre-clinical models

National Research Ethics Service (NRES)

Medicines & Healthcare Regulatory Authority (MHRA

Public-patient involvement/engagement

Commercialisation

National Institute for Health & Care Excellence (NICE) and Clinical Commissioning Groups (CCG) – Introduction to these organisations and how decisions are made to implement new technologies in the UK NHS

Funding clinical studies and commercialisation of research – introduction to the funding streams available for trialling new healthcare technologies and possible routes to commercialisation

4 Case studies

Tutorials based on a clinical problem where possible solutions will be explored. Students will work in multidisciplinary teams to design a clinical study which they will present.

Case studies may include:

Harnessing nanoclays for tissue regeneration

Intravascular ultrasound for diagnosis and treatment of coronary artery disease

Intelligent medical sensors for real-time disease monitoring

In vivo imaging of antibody therapies

Transferrable Skills

IT skills

Referencing

Communication skills

Oral presentation skills

Reflection

Multidisciplinary team working

Teaching and learning methods

A variety of learning and teaching methods will be adopted to promote a wide range of skills and meet the differing learning styles of the group.

The techniques will include seminars, practical demonstrations and exercises surrounding interpretation of data and clinical scenarios.

Specialist lecturers from a range of academic and health care professional backgrounds will be used to ensure a breadth and depth of perspective is offered, giving a good balance between background theories and principles and practical management advice.

Resources & Reading list

General Resources

Module Blackboard site TBC.

Internet Resources

ClinicalTrials.gov.

Assessment strategy

A qualifying mark of 40% on each assessed component of the module must be achieved to avoid an outright fail of the module. Each of the component marks is then combined, using the appropriate weighting, to give an overall mark for the module. If the overall mark is less than 50% when the weighting has been applied to the components, this constitutes a failure of the module.

Formative

This is how we’ll give you feedback as you are learning. It is not a formal test or exam.

Summative

This is how we’ll formally assess what you have learned in this module.

Referral

This is how we’ll assess you if you don’t meet the criteria to pass this module.

Repeat Information

Repeat type: Internal & External