Dr A. Emre Sayan PhD
- Related links
Dr A. Emre Sayan is Lecturer within Medicine at the University of Southampton.
Dr Sayan holds a Molecular Biology and Genetics (MBG) degree from Bogazici University (Istanbul, 1995). Then he completed his MSc. (1997) and PhD. (2002) degrees in Bilkent University (Ankara). Between 2002 and 2010, he did 3 post-doctoral trainings in France (INSERM U370, Paris) and UK (MRC Toxicology Unit, Leicester and University of Leicester, CSMM dept). Dr Sayan was appointed as a lecturer in Cancer Sciences Division at University of Southampton in 2010.
His research (between 1997 and 2010) comprised the role of p53 family member proteins (p53, p63 and p73) during normal physiology and cancer development. Additionally he developed interest in Epithelial-Mesenchymal Transition (EMT), a process key to the spread of tumor cells, which is implicated in metastasis and chemo-resistance. As metastasis is the primary reason for cancer related death, identification and characterization of EMT pathways is critical for patient stratification and development of new therapies.
Dr. Sayan leads a group that investigates chemo-resistance and metastasis mechanisms in solid cancers. He has been specialized in hepatocellular carcinoma, bladder carcinoma, breast cancer and colorectal carcinoma. His research is based in Cancer Sciences Division, Southampton General Hospital and he has strong collaborations with clinical oncologists, consultants and surgeons. He has more than 25 peer-reviewed articles, most of which, in journals such as Oncogene, PNAS, Cell Death and Diff., JBC and JCB.
BSc, Bogazici University, Istanbul, Turkey (1995)
MSc, and PD. Bilkent University, Ankara, Turkey (1997 and 2002)