MB BS, MRCP, FRCR, PhD
- Primary position:
- Senior Lecturer
- Other positions:
- Consultant Clinical Oncologist
Dr Andrew Bateman was appointed Senior Lecturer, Cancer Sciences, University of Southampton in 2002 and was recipient of a Cancer Research UK Clinician Scientist award. He had graduated from St Bartholomew’s Hospital Medical School in 1989 and undertaken general medical training in London and the South East. He was appointed to a Clinical Oncology Registrar Training post at the Hammersmith Hospital in 1993, spent a year (’95-’96) in Christchurch, New Zealand, completing the FRCR in ’97. He then entered research as an ICRF clinical research fellow in the laboratory of Dr Richard Vile, initially at the Hammersmith and then subsequently in the Molecular Medicine Program, Mayo Clinic, Rochester, Minnesota.
In 2001-2 Dr Bateman completed his Clinical Oncology training at Mount Vernon Hospital, before obtaining a CR UK Clinician Scientist Fellowship and moving to Southampton. Here he has developed a clinical practice in gastrointestinal malignancy, a focus in clinical trials, and research in cancer immunology and immunotherapy.
MB BS, University of London (1989)
MRCP, Royal College of Physicians (1992)
FRCR, Royal College of Radiologists (1997)
PhD, Open University (2002)
Clinical Research Fellow, Imperial Cancer Research Fund, 1997-98
Research Associate, Molecular Medicine Program, Mayo Clinic 1998-2001
Clinical Oncology Senior Registrar, Mount Vernon Hospital, 2001 – 2002
Senior Lecturer, Consultant Clinical Oncologist, University of Southampton 2002 - present
The University of Southampton's electronic library (e-prints)
Dr Andrew Bateman’s research is focused on understanding the tumour micro-environment, assessing potential predictive markers of response to conventional cancer treatments, as well as introducing novel therapies in to the clinic. These projects are conducted with relevance to gastro-intestinal cancers.
Adenocarcinoma of the oesophagus and oesophago-gastric junction has become the predominant histological tumour type seen in the UK. The majority of cases are thought to evolve through a process of metaplasia (Barrett’s), dysplasia and on to cancer. In conjunction with surgical and pathology colleagues we have built up a database of over 200 patients with matched clinical and pathology covering this spectrum of change in the lower oesophagus. This database is currently being interrogated. The work aims to identify potential drivers of malignant development, neo-antigen expression, predictors of response to neo-adjuvant therapy as well as assessment of the tumour micro-environment with particular focus on the immune environment. A longterm aim will be to design rational immunotherapy strategies for adjuvant treatment of oesophago-gastric cancer.
In collaboration with Professor Ottensmeier, Dr Bateman has recently obtained Cancer Research UK funding to conduct a Phase 2 DNA vaccine trial in advanced colorectal cancer: The Acacia Trial. This will be a randomized, multi-centre trial which will address the effectiveness of vaccination in this group, the interaction between vaccine and chemotherapy, and the advantage of a dual antigen vaccine strategy.
Dr Bateman is Clinical Lead of the Central South Coast Cancer Research Network (CSCCRN). The CSCCRN recruits large numbers of patients in to NIHR Trials across a broad range of cancer specific sub groups. Dr Bateman is also active in the radiation subgroup of the Upper GI site specific group and is involved in developing a Phase 2 study of neo-adjuvant chemoradiotherapy in oesophageal cancer.
Academic unit: Cancer Sciences Academic Unit
Affiliate academic units: Cancer Sciences Research group
Postgraduate student supervision
Mr Fergus Noble, FRCS
Ms Sarah Williams
Faculty of Medicine
FRCR Part 1 examiner 2005 - present
Dr Andrew Bateman
Faculty of Medicine University of Southampton Southampton General Hospital Mailpoint 801 South Academic Block Tremona Road Southampton SO16 6YD or Faculty of Medicine University of Southampton Building 85 Life Sciences Building Highfield Campus Southampton SO171BJ
Room Number: SGH/CSB CS,D13/MP82