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The University of Southampton
Medicine

How strong do you think you are? British studies shine light on how strength changes across life

Published: 4 December 2014

Researchers from the Medical Research Council Lifecourse Epidemiology Unit (MRC LEU), University of Southampton have shed new light on how grip strength changes across the lifespan. Previous work has shown that people with weaker grip strength in midlife and early old age are more likely to develop problems, such as loss of independence and to have shorter life expectancy. However, there is little information on what might be considered a normal grip strength at different ages.

This latest research, which combined information from 12 British studies and is published in PLOS ONE, included grip strength readings from 49,964 participants aged from four years old to 90 and above, and combined them to produce reference charts.

Lead author, Dr Richard Dodds, Wellcome Trust Research Training Fellow at the MRC LEU at the University of Southampton, comments: “We found that men were typically stronger than women from adolescence onwards, but both men and women reached a peak level of strength during their thirties before becoming weaker with age. We are now clear about the range of normal strength in young adults and have used this information to propose levels below which an older person would be considered to have weak grip strength.”

GPs or hospital doctors could use the information in this study to help interpret measurements of grip strength and to identify those at risk of frailty and loss of independence.

Avan Aihie Sayer, Professor of Geriatric Medicine, at the MRC LEU at the University of Southampton, who oversaw this work, adds: “Sarcopenia, the loss of skeletal muscle mass and function with age, is an area of intense research activity and is being increasingly recognised in clinical practice. Grip strength has been recommended for the assessment of muscle strength in the clinical setting and this study will aid the recognition of important conditions such as sarcopenia and frailty.”

Cyrus Cooper, Professor of Rheumatology and Director of the MRC LEU at the University of Southampton where the research was carried out, adds: “This study forms part of a larger programme of research at the MRC Lifecourse Epidemiology Unit at the University of Southampton. Three of the twelve studies are based here at the Unit where one of our aims is to understand the causes across the lifecourse of common musculoskeletal conditions, including sarcopenia.”

Notes for editors

1. A copy of the paper entitled Grip strength across the life course: normative data from twelve British studies is available at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113637

2. The Medical Research Council has been at the forefront of scientific discovery to improve human health. Founded in 1913 to tackle tuberculosis, the MRC now invests taxpayers’ money in some of the best medical research in the world across every area of health. Twenty-nine MRC-funded researchers have won Nobel prizes in a wide range of disciplines, and MRC scientists have been behind such diverse discoveries as vitamins, the structure of DNA and the link between smoking and cancer, as well as achievements such as pioneering the use of randomised controlled trials, the invention of MRI scanning, and the development of a group of antibodies used in the making of some of the most successful drugs ever developed. Today, MRC-funded scientists tackle some of the greatest health problems facing humanity in the 21st century, from the rising tide of chronic diseases associated with ageing to the threats posed by rapidly mutating micro-organisms. http://www.mrc.ac.uk/

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