Infections and Exacerbators of Chronic Lung Disease
Weds 11th July 2012
1800-2000 Welcome Reception
Thursday 12th July 2012
0800-0845 Registration and Coffee
0845-0900 Welcome address Professor Don Nutbeam, Vice-Chancellor of the University of Southampton
0900 –1030 Session 1: Asthma Exacerbations
0900-0925 Professor Sebastian L Johnston (Imperial College, London, UK)
“Lessons learnt from human models of asthma exacerbations”
0925-0950 Professor Tracey Hussell (University of Manchester, UK)
“Resolution of inflammatory lung disease: the epithelium is in control”
0950-1015 Dr Peter Howarth (University of Southampton, UK)
“Airway bacterial colonisation in asthma and the exacerbation prone phenotype”
1015-1030 Free Communication 1: Dr Hitasha Rupani (University of Southampton, UK)
“MicroRNA regulation of Toll-like receptor 7 function in severe asthma: relevance to viral responses”
1030-1100 Tea
1100 –1215 Session 2: COPD Exacerbations
1100-1125 Professor Jürgen Lohmeyer (University of Geissen, Germany)
“Phagocyte-epithelium cross talk in acute and chronic lung inflammation”
1125-1150 Dr Tom Wilkinson (University of Southampton, UK)
“Investigating the role of mucosal infection in the natural history of COPD”
1150-1215 Dr Mona Bafadhel (University of Leicester, UK)
“Characterising COPD exacerbations and treatment applications”
1215-1230 Free Communication 2: Dr James Garnett, (St George’s University of London, UK)
“Metformin reduces transepithelial glucose permeability and inhibits the hyperglyecemia associated growth of Staphylococcus aureus in the airway”
1230-1330 Lunch & poster viewing session
1330 –1500 Session 3: Infections in Fibrotic Lung Diseases
1330-1355 Dr Gisli Jenkins (University of Nottingham, UK)
“The pathogenesis of IPF and a potential role for influenza induced acute exacerbations”
1355-1420 Professor Stuart Elborn (Queen’s University Belfast, UK)
“Cystic fibrosis: Microbiota, exacerbations and CFTR function”
1420-1445 Dr Adrian Martineau (Queen Mary, University of London, UK)
“Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment”
1445-1500 Free Communication 3: Dr Chris Scotton (University College London, UK)
“Ex vivo micro-CT analysis of bleomycin-induced lung fibrosis for pre-clinical drug evaluation”
1500-1530 Tea
1530 – 1630 Young Investigator Award Presentations - Chair: Professor Iain Cameron (Dean, University of Southampton Faculty of Medicine)
1530-1545 Dr Kevin Goss (University of Southampton, UK)
“Dynamic lipidomic mass spectrometry of endotracheal secretions and plasma from preterm infants mechanically ventilated on the neonatal intensive care unit”
1545-1600 Lisa Jolly (University of Nottingham, UK)
“H1N1-mediated TGFβ activation involves TLR3, RHO A and αVβ6-integrin in human bronchial epithelial cells”
1600-1615 Dr Katrina McNulty (University College London, UK)
“Longitudinal bioluminescence tracking of exogenously delivered macrophages in the lungs of injured mice: potential candidates for cell therapy?”
1615-1630 Dr Amanda Tatler (University of Nottingham, UK)
“Enhanced integrin αvβ6 expression by transcriptional regulation of the β6 subunit via SMAD3”
1630-1730 Keynote Address: Professor Stephen Holgate, CBE (University of Southampton, UK)
“Stratified approaches for reclassifying asthma along mechanistic pathways for the targeting of novel therapies”
1730 BALR AGM
1900 Coaches to collect delegates for transport to conference dinner
1930 Dinner at Dolphin Hotel, Southampton
2200 Presentation of Awards
2230 Coaches to collect delegates for transport to accommodation
Friday 13th July 2012
0930 –1030 Session 4: Developing new treatments
0930-0955 Professor Donna Davies (University of Southampton, UK)
“Human in vitro models for the study of asthma and other lung diseases: why and how?”
0955-1020 Dr Robert Snelgrove (Imperial College, London, UK)
“Leukotriene A4 hydrolase: an anti-inflammatory role for a pro-inflammatory enzyme”
1020-1045 Dr Donna Finch (MedImmune, UK)
“Treating exacerbations of COPD with novel biologic therapeutics”
1045-1110 Professor Sir Andrew McMichael, FRS (University of Oxford, UK)
“Anti-viral T cells”
1110-1140 Tea
Teatime seminar by BD Biosciences – “Multicolour Flow Cytometry made easier: New BD fluorochromes”
1140 –1300 Session 5: Infection as a cause of chronic lung disease
1140-1205 Prof Michael Holtzman (Washington University, USA)
“Stateside progress on asthma and COPD”
1205-1230 Prof Peter Openshaw (Imperial College, London, UK)
“Delayed effects of childhood infections: what are the possible mechanisms?”
1230-1255 Prof Hans Bisgaard (University of Copenhagen, Denmark)
“The Human Microbiome in the Origins of Asthma & Atopy”
1255-1300 Closing remarks
1300 Lunch & Departure
