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Miss Gemma Fryatt MSc, BSc

Research Technician in Neuroimmunology

Miss Gemma Fryatt is Research Technician in Neuroimmunology within Biological Sciences at the University of Southampton.

Career History

2014-present: Research Technician, University of Southampton, UK.

Academic Qualifications

2012–2014: MSc Neuroscience in Neurodegeneration. King’s College London, UK.
2005–2008: BSc (Hons) Forensic Biology. University of Portsmouth, UK.

Research

Publications

Contact

Research interests

My research interests focus on Neurodegeneration.

Research group

Biomedical Sciences

Affiliate research group

Southampton Neuroscience Group (SoNG)

Research project(s)

Understanding the role of early-life inflammation on the incidence of Alzheimer’s disease

This project aims to investigate the impact of early-life systemic inflammation on the onset and progression of Alzheimer’s disease.

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Articles

Hu, Y., Fryatt, G. L., Ghorbani, M., Obst, J., Menassa, D., Martin estebane, M., Muntslag, T. A. O., Olmos alonso, A., Guerrero Carrasco, M., Thomas, D., Cragg, M., & Gomez-Nicola, D. (2021). Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology. Cell Reports. https://doi.org/10.1101/2021.03.22.436174
Chacon-De-La-Rocha, I., Fryatt, G. L., Rivera, A. D., Restani, L., Caleo, M., Gomez-Nicola, D., & Butt, A. M. (2021). The synaptic blocker botulinum toxin A decreases the density and complexity of oligodendrocyte precursor cells in the adult mouse hippocampus. Journal of Neuroscience Research, 99(9), 2216-2227. https://doi.org/10.1002/jnr.24856
Chacon-De La Rocha, I., Fryatt, G., Rivera, A. D., Verkhratsky, A., Raineteau, O., Gomez-Nicola, D., & Butt, A. M. (2020). Accelerated dystrophy and decay of oligodendrocyte precursor cells in the APP/PS1 model of Alzheimer's-like pathology. Frontiers in Cellular Neuroscience, 14, [575082]. https://doi.org/10.3389/fncel.2020.575082
Mancuso, R., Fryatt, G., Cleal, M. E., Obst, J., Pipi, E., Monzon-Sandoval, J., Ribe, E., Winchester, L., Webber, C., Nevado, A., Jacobs, T., Austin, N., Theunis, C., Grauwen, K., Ruiz Ortega, E. D., Mudher, A., Vicente-Rodriquez, M., Parker, C., Simmons, C., ... Perry, V. H. (2019). CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice. Brain, 142(10), 3243-3264. https://doi.org/10.1093/brain/awz241

Book Chapter

Gomez-Nicola, D., Fryatt, G. L., & Askew, K. E. (2019). Measuring microglial turnover in the adult brain. In O. Garaschuk, & A. Verkhratsky (Eds.), Microglia (Vol. 2034, pp. 207-215). (Methods in Molecular Biology). Humana. https://doi.org/10.1007/978-1-4939-9658-2_15

Miss Gemma Fryatt
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

Room Number : 9500 SGH/LF83/MP12

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