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The University of Southampton
Biological Sciences
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Dr Jane Gibson BSc, MSc, PhD

Lecturer in Bioinformatics, Principal Investigator in Bioinformatics and Genomics, Theme Leader: Computational and Systems Biology, Chair of the BioSci IT Strategy Group

Dr Jane Gibson's photo

Dr Jane Gibson is Lecturer in Bioinformatics within Biological Sciences at the University of Southampton.

Career History

2013-present: Lecturer in Bioinformatics. Biological Sciences, University of Southampton, UK.
2012-2013: Career track award Fellow. Faculty of Medicine, University of Southampton, UK.
2008-2012: Postdoctoral research assistant. School of Medicine, University of Southampton, UK.
2002-2008: Research assistant. School of Medicine, University of Southampton, UK.

Academic Qualifications

2015: PGCAP (Merit) Postgraduate certificate in Academic Practice. University of Southampton, UK.
2008: PhD Genetic Epidemiology and Bioinformatics. University of Southampton, UK.
2002: MSc Biosystems and Informatics.  University of Liverpool, UK.
2001: BSc (Hons) Genetics.  University of Leeds, UK.

Research interests

My research involves statistical genetics and bioinformatics approaches to understanding the human genome and the changes which can lead to disease. Research areas include:

  • Studies which aim to determine genes underlying ophthalmic traits such as Age-related Macular Degeneration, Primary Open Angle Glaucoma and Nystagmus. This involves next generation sequencing and genetic association studies and (with Andrew Lotery, Jay Self & Sarah Ennis, Faculty of Medicine).
  • Analysis of tumour samples to determine somatic variants from exome and targeted gene sequencing approaches in cancer patients (with Jon Strefford, Faculty of Medicine).
  • The determination and characterisation of linkage disequilibrium patterns and homozygous regions in disease and population studies.
  • The development of in-house tools and software pipelines to enable streamlined bioinformatic analyses of next generation sequencing data.
  • Identifying genes causing Mendelian diseases and detection of susceptibility genes involved in familial cancers using exome sequencing (with colleagues at Wessex Clinical Genetics Service).
  • Analysis of genomic and transcriptomic data investigating domestciation of crop species (with Mark Chapman, BioSci)

PhD Supervision

Roshan Sood (2014-2018)
Project Title: Interpreting large-scale next generation sequence data using bioinformatic approaches.
Funding: Mayflower studentship

Luke O’Gorman (2015-2018) Co-Supervisor
Project Title: The Development of Bioinformatic Pipelines for Ophthalmic Disease
Funding: Gift of sight studentship

Gaia Andreoletti (Awarded 2016) Co-supervisor
Project Title: Genomic analyses of paediatric inflammatory bowel disease
Funding: Kerkut Trust and CICRA studentships

Reuben Pengelly (Awarded 2015) Co-supervisor
Project Title: Genomic data analysis: populations, patients and pipelines
Funding: Faculty of Medicine doctoral training award and donation

Research group

Computational and Systems Biology

Affiliate research groups

Molecular and Cellular Biosciences, Institute for Life Sciences, Computational Modelling Group

Research project(s)

A genome-wide approach to understand domestication

Harnessing genomic technologies to investigate how humans have altered the genomes of wild plants into the crops we see today.

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Module Co-ordinator & Lecturer

BIOL2013 Bioinformatics and DNA technology
BIOL6055 Computational Biology

Module Co-ordinator and Project Supervisor

BIOL3069 In silico research project


BIOL3063/6074 Bioinformatics and Systems Biology
BIOL3064/6071 Cancer and Chromosome Biology
MEDI6215 Bioinformatics, Interpretation and Data Quality Assurance in Genome Analysis

Personal Tutor

BIOL1020 Core Skills in the Life Sciences


BIOL-BNBP Year 2 BNBP Tutorials

University of Southampton

Computational and Systems Biology Theme Leader
Chair of the BioSci IT Strategy Group
Proteomics Steering Group member
Research Strategy Group member
Academic library representative
Academic liaison for the BioSci website
Faculty representative, DataScience@Southampton board

Dr Jane Gibson
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ

Room Number: 85/6041

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