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The University of Southampton
Biological Sciences
Email:
J.Pally@soton.ac.uk

Dr Joseph M Pally Dip, B-Tech, MSc, MRes, PhD

Research Fellow

Dr Joseph M Pally's photo

Dr Joseph Pally is a Research Fellow in Mammary Epithelial Cell Divisions, within the School of Biological Sciences, University of Southampton.

Career History

Oct 2020- Present: Research fellow for Dr Salah Elias focusing on Mammary Stem Cell Division and High-Res 3D Imaging 

Feb 2020- Aug 2020: Research fellow in Cell Biology and Smart Materials at Nottingham Trent University

March 2018- Jan 2020 Science and Technology Research assistant for Prof Bob Stevens at Nottingham Trent University

Feb 2013- Aug 2013 Lab Assistant at Global Labs, Des Plaines, Illinois, USA

Sept 2009- March 2010 Technical assistance at Frontier Lifeline hospital, Chennai, India

July 2008- June 2009 Lab assistant for biotechnology and protein engineering labs at SRM University

Academic Qualifications

Feb 2015- Dec 2019 PhD in Science and Technology focusing on Cell Biology, Biophysics and Medical implant therapies at Nottingham Trent University, Nottingham, UK

Sept 2013- Sept 2014 MRes. Neuroscience at Nottingham Trent University, Nottingham, UK

Sept 2011- Sept 2012 MSc. Molecular cell biology at Nottingham Trent University, Nottingham, UK

July 2006- July 2010 B-Tech. Genetic Engineering at SRM University, Chennai, India

July 2007- July 2008(PT) Diploma in Java programming and computer hardware and software engineering at CSC, Chennai, India 

Research interests

  • Cell Biology
  • Cancer Biology
  • 3D Cell Culturing
  • Microscopy
  • Neuroscience
  • Nanofibre Technology
  • Medical Devices & Implantable Technologies

Do oriented cell division dictate fate decisions in Mammary stem cells?

The Project focuses on 1) how mitotic spindle dynamics and orientation, cell polarity and chromosome segregation are controlled in the mammary epithelium; 2) how these mechanisms act together to influence cell fate and behaviour; 3) and how their dysregulation leads to malignant transformation.

Multidisciplinary approaches such as single-cell genetic lineage tracing in genetically engineered mice in conjunction with high-resolution 3D imaging and mathematical/computational modelling; mammary organoids; biochemistry and live cell imaging; proteomics; and next generation sequencing are used in this project.

Research group

Developmental Biology

Research project(s)

Do oriented divisions dictate fate decisions in mammary stem cells?

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Dr Joseph M Pally
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

Room Number: 85/Level 6/M55

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