The University of Southampton
Biological Sciences
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 Juliane Obst Dipl.-Biol.

Senior Research Assistant in Neuroimmunology

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Juliane Obst is Senior Research Assistant in Neuroimmunology within Biological Sciences at the University of Southampton.

Career History:

2015-present: Senior Research Assistant. University of Southampton, UK
2011-2015: PhD Student in Medical Neurosciences. Charite-Universitaetsmedizin Berlin, Germany
2004-2009: Studies of biology. University of Leipzig, Germany

Academic Qualifications:

2009 “Diplom-Biologist” (advanced degree in Biology)




Research interests

My research interests focus on inflammatory processes in neurodegenerative diseases, including prion and Alzheimer’s disease. Our main goal is to address how microglial cells contribute to these pathologies and to test the efficacy of innovative therapeutic approaches in modulating markers of central inflammation.

Research group

Biomedical Sciences

Research project(s)

Regulation of microglial proliferation during chronic neurodegeneration

An important aspect of chronic neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's and prion disease, is the generation of an innate inflammatory response within the central nervous system (CNS).

Inflammation in chronic neurodegeneration and the contribution of systemic inflammation

We are investigating the microglia activation in a model of prion disease, mouse scrapie.

Control of adult neurogenesis during chronic neurodegeneration

Neurogenesis is increased during acute and chronic neurodegeneration, with the potential to replace damaged neurons at the sites of neuronal loss.

Understanding oligodendrocyte progenitor dynamics and myelin loss in Alzheimer’s Disease

Oligodendrocyte progenitor cells (OPCs) may be altered in Alzheimer’s disease.



Juliane Obst
Biological Sciences
Faculty of Natural & Environmental Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ

Room Number:SGH/LD30/MP840

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