The University of Southampton
Biological Sciences

Dr Zahid Shah Phd

Research Fellow

Dr Zahid Shah's photo
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Dr Zahid Shah is Research Fellow within Biological Sciences at the University of Southampton.

Career history

2014-Present: Research Fellow. Inositide laboratory, Biological Sciences, University of Southampton, UK.
2011-2113: Postdoctoral Scientist. CRUK Inositide laboratory, Cancer Research UK Manchester Institute, University of Manchester, UK.
2008-2011: Senior Research Associate. P53 Research Unit, University of York, UK.
2006-2008: Senior Research Fellow. Cancer Sciences Division, University of Southampton, UK.
1996-2006: Finnish Academy Research Fellow/Senior Research Associate. Institute of Biomedical Technology, University of Tampere, Finland.
1995-1996: Research Assistant. Institute of Biotechnology, University of Cambridge.

Academic qualifications

1995: PhD. University of Cambridge, UK.





Research interests

Phosphoinositides control various cellular functions such as membrane trafficking and endocytosis and in doing so impact upon cell proliferation and apoptosis. These lipids are also present in the nucleus where their function is not completely understood. Their levels in the nucleus changes in response to external environmental inputs and some studies have implicated these changes in the regulation of nuclear functions such as transcription. We aim to understand how these lipids are regulated and what downstream functions are regulated by changes in their levels.

Research group

Molecular and Cellular Biosciences

Research project(s)

Nuclear phosphoinositides and their role in the regulation of myogenic differentiation

Nuclear PI5P regulates the basal transcription complex by interacting with the PHD finger of TAF3. Deregulation of TAF3 by PI5P interaction impacts on muscle cell differentiation.

The regulation of epigenetic signalling by nuclear phosphoinositides

Epigenetic signalling and nuclear phosphoinositides.


Professional Affiliations

2012-Present: Member Editorial Board ISRN Cell Biology
2003-2005: Finnish Academy Research Fellowship. Models of mitochondrial disease

Dr Zahid Shah
Biological Sciences
Faculty of Natural & Environmental Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ

Room Number:85/4041/21

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