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The University of Southampton
Biological Sciences

Transcriptions and RNA Fate Event

Transcriptions and RNA Fate
Time:
13:00 - 14:00
Date:
1 March 2017
Venue:
Life Sciences Building 85, Room 2207, Highfield Campus

For more information regarding this event, please telephone Selina Barry on 24794 or email S.J.Barry@soton.ac.uk .

Event details

Biological Sciences Seminar Series Programme 2016 - 2017

Abstract: Eukaryotic genomes are pervasively transcribed on both strands and, in addition to the pre-mRNAs, there is extensive antisense transcription, transcription over promoters, and overlapping transcription between convergent genes and genes organized in tandem. Analyzing nascent transcription at high resolution during the yeast metabolic cycle uncovers evidence for extensive transcriptional interference between genes. Furthermore, we show that antisense transcription alters the chromatin structure and this influences the fate of the encoded transcripts. The new relationship between transcription and RNA fate will be discussed.

 

 

Speaker information

Professor Jane Miller,University of Oxford,Professor Jane Mellor in the Biochemistry Department has been elected as a member of the European Molecular Biology Organisation (EMBO). She is one of 66 leading life scientists to be honoured with the award and joins a membership of just over 1400 of the world's foremost molecular biologists

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