Interwoven LiveSite https://www.southampton.ac.uk/biosci/news/seminars/latest.pageBioSciences Seminarshttps://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/07/29_prof_sumiko_mochida.pageMon, 29 Jul 2013 00:00:00 +0100 [13:00, 29 July 2013] Professor Mochida has a long standing interest in the molecular and cellular mechanisms that co-ordinate Ca2+channel function and how ion influx co-ordinates the exocytosis of neurotransmitterhttps://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/05/13_dr_jack_mellor.pageMon, 13 May 2013 00:00:00 +0100 [17:00, 13 May 2013] Mossy fibre synapses between dentate granule cells and CA3 pyramidal neurons in the hippocampus have unique and fascinating structural and functional properties.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/04/29_ken_norris.pageMon, 29 Apr 2013 00:00:00 +0100 [17:00, 29 April 2013] Understanding how biodiversity is responding to environmental change is, in part, a problem in population biology.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/04/22_dr_niall_mcnamara.pageMon, 22 Apr 2013 00:00:00 +0100 [16:00, 22 April 2013] Climate change impacts resulting from fossil fuel combustion and concerns about the diversity of energy supply are driving interest to find low-carbon energy alternatives. As a result bioenergy is receiving widespread scientific, political and media attention for its potential role in both supplying energy and mitigating greenhouse (GHG) emissions. https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/04/15_professor_thomas_lynch.pageMon, 15 Apr 2013 00:00:00 +0100 [17:00, 15 April 2013] Since Darwin's (1872/1965) seminal book The Expression of the Emotions in Man and Animals a number of theorists and researchers have argued that emotions evolved to communicate. However, most treatment approaches have tended to overlook this observation as science became increasingly sophisticated in investigating a person's internal experience (e.g., cognition, physiology, attention, neurobiology). https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/03/4_professor_karl_swann.pageMon, 04 Mar 2013 00:00:00 +0000 [17:00, 4 March 2013] At fertilization in all mammals the sperm causes egg activation by triggering a series of intracellular Ca2+ oscillations. We have shown that these Ca2+ oscillations can be triggered by a sperm specific protein called phospholipase C zeta (PLCzeta).https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/02/25_dr_kevin_staras.pageMon, 25 Feb 2013 00:00:00 +0000 [17:00, 25 February 2013] At small central synapses, recycling of synaptic vesicles is a key step in stimulus-driven transmission. Exactly how the structure of a recycling vesicle population at a terminal relates to its functional role remains unclear, however.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/02/18_professor_liliane_schoofs.pageMon, 18 Feb 2013 00:00:00 +0000 [17:00, 18 February 2013] Neuropeptides are small regulatory proteins that have a key role in the functioning of the brain and nervous system and are involved in reproduction, development, (learning) behaviour, digestion, excretion, locomotion, circadian clock regulation.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/02/11_dr_noel_wortham.pageMon, 11 Feb 2013 00:00:00 +0000 [17:00, 11 February 2013] Regulation of protein synthesis is a key factor in cell growth and division, and organ homeostasis. Its regulation allows both individual cells and organisms to respond quickly to changes in nutrient and signalling status.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/02/4_dr_reinmar_hager.pageMon, 04 Feb 2013 00:00:00 +0000 [17:00, 4 February 2013] Epigenetic mechanisms are now recognized as a fundamental source of variation for most phenotypes, not caused by differences in genotype, and thus acting as a separate or bridging layer between genetic and phenotypic variation.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2013/01/28_dr_chris_connolly.pageMon, 28 Jan 2013 00:00:00 +0000 [17:00, 28 January 2013] This talk will discuss the acute and chronic changes to neurotransmitter receptor function in the honeybee following exposure to pesticide agonists.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/12/10_professor_graham_burton.pageMon, 10 Dec 2012 00:00:00 +0000 [17:00, 10 December 2012] Intrauterine growth restriction (IUGR) is a serious condition, affecting around 10% of pregnancies in the UK and leading to increased risk of perinatal death and chronic disease through developmental programming. https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/12/3_professor_anne_willis.pageMon, 03 Dec 2012 00:00:00 +0000 [17:00, 3 December 2012] Under conditions of patho-physiological cell stress post transcriptional regulation of gene expression is achieved by the reprogramming protein synthesis. For example, we have shown post-transcriptional control makes a major contribution to overall gene expression changes that occur during the regulation of apoptosis by TRAIL and following exposure of cells to DNA damaging agents. This regulation is brought about by interaction of RNA-binding proteins with specific regulatory elements in their cognate mRNAs that control mRNA stability and translation.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/11/26_professor_martin_glennie.pageMon, 26 Nov 2012 00:00:00 +0000 [17:00, 26 November 2012] Professor Glennie from the Faculty of Medicine will talk about his work concerning the therapeutic potential of the immune system for cancer treatment.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/11/19_dr_mike_murphy.pageMon, 19 Nov 2012 00:00:00 +0000 [17:00, 19 November 2012] Mitochondrial production of reactive oxygen species (ROS) contributes to many cell processes. Consequently there is a need to develop specific tools to manipulate mitochondrial ROS production and oxidative damage. Here I report on the development of novel antioxidants that selectively block some aspects of mitochondrial oxidative damage, enabling the roles of mitochondrial oxidative stress to be inferred.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/11/12_dr_paul_driscoll.pageMon, 12 Nov 2012 00:00:00 +0000 [17:00, 12 November 2012] Phosphatidylinositol-phospholipase Cs (PI-PLCs) constitute a critical component of second messenger-generating system that operates downstream of a great number of cell surface receptors, important for development, cell proliferation and motility (and possibly cell death). Dysregulation of these enzymes is associated with various pathological conditions.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/11/8_microglia_and_systemic_inflammation.pageThu, 08 Nov 2012 00:00:00 +0000 [17:00, 8 November 2012] The Southampton Neuroscience Group presents this seminar with Dr Jessica Teelinghttps://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/11/5_the_omics_of_uv_photoprotection_on_the_australian_great_barrier_reef.pageMon, 05 Nov 2012 00:00:00 +0000 [16:00, 5 November 2012] In marine environments where nutrient concentrations are often poor, sessile invertebrates compensate for a lack of nutrients by adopting a symbiotic relationship with microorganisms, especially endosymbiotic dinoflagellates and unicellular algae. In photoautotrophic symbiosis, organic carbon is released to the animal host for nutrition by the microorganism that benefits by recycling carbon dioxide from the host for photosynthesis. https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/10/22_spatial_and_temporal_regulation_of_neuronal_subtype_differentiation_.pageMon, 22 Oct 2012 00:00:00 +0100 [17:00, 22 October 2012] Dr Douglas Allan will present his recent findings on this subject, drawn from his study of fruit flies, Drosophila melanogaster.https://cdn.southampton.ac.ukhttps://www.southampton.ac.uk/biosci/news/seminars/2012/10/15_galleria_mellonella_as_an_alternative_animal_infection_model.pageMon, 15 Oct 2012 00:00:00 +0100 [17:00, 15 October 2012] Pathogenic bacteria are becoming an increasing burden as the ability of established antibiotics to act against them becomes blunted. Approaches designed to investigate such bacteria place a high demand on animal use and there is a real desire to drive the development of model systems that allow researchers to unpick pathological mechanism and treatments against this.