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The University of Southampton
Biological SciencesPostgraduate study

Miss Charlotte Hill MEng

Postgraduate Research Student in Biological Sciences

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Charlotte Hill is a Postgraduate Research Student within Biological Sciences at the University of Southampton.

Academic Qualifications

2010-2016: MEng Chemical Engineering. University of Surrey, UK.

Research interests

Previous research as part of a masters research project involved understanding the relationship between anticancer drugs, radiotherapy and autophagy-inhibitors on pancreatic cancer.

Current research will be focused on developing further understanding on the regulation of epithelial-mesenchymal transition (EMT) and further dissecting the pathways which are involved in this process. Understanding how these pathways affect the metastic ability and invasiveness of tumours, and the role which autophagy plays in this process.

PhD Supervision: Dr Yihua Wang & Dr Andrew Steele
PhD Research: Role of autophagy in the regulation of epithelial-mesenchymal transition (EMT), invasion and metastasis in RAS-mutated tumour
Funding: The Gerald Kerkut Charitable Trust & University's Central VC Scholarship Scheme

Research group

Molecular and Cellular Biosciences

Affiliate research group

Institute for Life Sciences

Research project(s)

How does autophagy regulate the development of idiopathic pulmonary fibrosis (IPF)?

Autophagy is a highly conserved and tightly regulated cellular process involved in the turnover of cytoplasmic organelles and proteins through a lysosome-dependent degradation process. The aim of this project is to understand the role of autophagy in the development of idiopathic pulmonary fibrosis (IPF), a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause.

Role of autophagy in oncogenic RAS-induced invasive behaviour

This project aims to understand the role of autophagy in oncogenic RAS-induced tumour invasion.

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Miss Charlotte Hill
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ
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