2017-present: PhD studentship. University of Southampton, UK
2014-2017: BSc (Hons) Biochemistry. University of Southampton, UK
PhD Research: Mechanistic insight into the regulatory role of the key kinetochore protein Spc105/KNL1 in chromosome segregation
Supervisors: Dr Marcin Przewloka and Dr Paul Skipp
Molecular and Cellular Biosciences
A large and mostly unstructured protein Spc105/KNL1 is an essential element of the eukaryotic kinetochore. The project addresses a question of how this protein performs its function as a binding platform for multiple regulatory components to control the proper chromosome segregation during mitosis.