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The University of Southampton
Biological SciencesPostgraduate study

Miss Isabel Hughes BSc (Hons)

MRes Advanced Biological Science student

Miss Isabel Hughes's photo

Isabel Hughes is an MRes Advanced Biological Science student within the School of Biological Sciences at the University of Southampton.

Graduated in 2020 with a BSc (Hons) in Biomedical Sciences from the University of Southampton. I have a particular interest in microbiology, focussing my third-year dissertation project on the contribution of biofilms to antibiotic resistance of E. coli. This project explored the effect of subinhibitory antibiotic concentrations on the induction of biofilm formation.

Research interests

After a short summer project focussing on biofilm realted bacterial infections in 2019 I gained further interest and knowledge in microbiology. I applied this to my dissertation using many of the techniques I had learned during summer and further research strengthened my interest in infectious diseases and immunology.

I am now focussing on neuroimmunology; specifically the response of the immune system to tau pathology in Alzheimer’s Disease. I am looking at the impact of systemic salmonella infections on the propagation of tau pathology through the activation of the immune system and breakdown of the blood brain barrier. This project is combining my prior microbiology knowledge while also challenging me in a new field of neuroimmunology.

Why I chose MRes Advanced Biological Science

I chose an MRes in Advanced Biological Science due to the research-intensive nature of the course. A full 12 months in the lab allows me to practice essential laboratory skills in planning, preparing and carrying out experiments. Thus, allowing me to reach my ultimate career goal; contributing to the advancement of scientific understanding.

Aims for the future

Following graduation, I am looking to pursue a PhD in immunology and infection.


Dr Jessica Teeling
Dr Neil Smyth

Research group


Affiliate research group

MRes Advanced Biological Science

Miss Isabel Hughes
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ

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