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The University of Southampton
Biological SciencesPostgraduate study

Mr Paul Shefferd 

MRes Advanced Biological Science Student

Mr Paul Shefferd's photo

Paul Shefferd is an MRes Advanced Biological Science student within the School of Biological Sciences at the University of Southampton.

I graduated from Oxford Brookes University in 2019 with a first class honours degree in BSc Biological Science.

My dissertation focus was designing and refining a High Performance Liquid Chromatography protocol that could quantify the uptake of a marker peptidomimetic by the human PepT1 transporter when expressed in Xenopus laevis oocytes. This offered a new way to examine the relatively poorly understood mechanisms of hPepT1 translocation.

Research interests

I will be investigating the effect of opportunistic ESKAPE bacteria on the behavioural patterns of C. elegans worms. I will be observing how the nematodes respond variably to different strains of ESKAPE bacteria, particularly K. pneumoniae, and which neural circuits may be implicated in this response.

I chose MRes Advanced Biological Science because I can tailor the course to my interest in parasites and their interaction with hosts and vectors. The opportunity to undertake an extensive research project was also exciting to me after I enjoyed my undergraduate research project so much.

My aims for the immediate future are to develop my research and lab skills and to use this year as a way to determine whether or not a PhD would be a good next step.

Supervisors: Lindy Holden-Dye and Vincent O’Connor

Research group


Affiliate research group

MRes Advanced Biological Science

Mr Paul Shefferd
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ
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