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The University of Southampton
Biological Sciences

Research project: Uncovering the molecular mechanisms of asymmetric cell divisions in the adult mammary epithelium

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Project type: 

Applying proteomics, bioinformatics and cutting-edge molecular and imaging techniques to uncover the mechanisms of asymmetric cell divisions (ACDs) during mammary gland development and homeostasis, and the mechanisms of epithelial differentiation and architecture.

This project utilises a combination of 3D organoids, CRISPR-based gene editing, proteomics and mass-spectrometry to identify novel proteins that control oriented cell divisions in the mammary epithelium.

Principal Investigator & Supervisors:

Dr. Salah Elias

Funding provider:

Wellcome Trust

Funding dates:

03/12/2018 – 02/12/2020

Grant Code:


Related research groups

Developmental Biology
Molecular and Cellular Biosciences
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