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The University of Southampton
Biological Sciences

Dr C Howard Barton BSc, PhD

Reader in Biomedical Sciences, Principal Investigator Biomedical Sciences

Dr C Howard Barton's photo

Dr Howard Barton joined Biological Sciences in December 1994 having undertaken post-doctoral positions in both London and Cambridge UK and gaining experience in mammalian molecular cell biology.

Career History

1994-present: Reader in Biochemistry & Molecular Biology. University of Southampton, UK.
1990-1994: Research Fellow. London School of Hygiene and Tropical Medicine (LSHTM), University of Cambridge and Addenbrooke's Hospital, Department of Medicine, UK.
1985-1990: Research Fellow. Institute of Neurology, University of London and Guy's Hospital UMDS, University of London, UK.

Academic Qualifications

1982-1987: PhD in Biochemistry. University of Sheffield, UK.
1979-1982: BSc in Chemistry/Biochemistry (Jt.Hons). University of Nottingham, UK.

Research interests

Research interests

I have an interest in transport processes in immune cells, including their genetic regulation (Nramp1, Slc11a1) and more recently, in collaboration with Prof Malcolm East, in the regulation of transport by non-annular phospholipids. Such studies have been directed to drug transporters in bacteria, S.aureus (SAV1866), and a mammalian drug transporter homologue in M.musculus (ABCB1a/b). The latter has been implicated in the failure of therapeutic drugs and should specific regulatory phospholipid binding sites be identified these could constitute sites for attenuating drug resistance.

Research group

Molecular and Cellular Biosciences

Module co-ordinator:

BIOL1013 Integrative Mammalian Physiology.
BIOL2010 Molecular and Cellular Biochemistry: the flow of genetic information.
BIOL2022 Immunology, inflammation & infection
BIOL3034 Third year laboratory project

Professional responsibilities

Exam Officer

Dr C Howard Barton
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ

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