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The University of Southampton
Biological Sciences
Phone:
(023) 8059 8143
Email:
D.A.Rusling@soton.ac.uk

Dr David Rusling BSc, PhD

Research Fellow

Dr David Rusling's photo

Dr David Rusling is Research Fellow within Biological Sciences at the University of Southampton.

BSc (Biochemistry and Pharmacology) University of Southampton

PhD (Biochemistry) University of Southampton;

Post-doctoral Assistant 2005-8; University of Southampton

Post-doctoral Associate 2008-10; University of Bristol

Researcher Co-Investigator 2010-present; University of Southampton

Research interests

My research concerns the structure, function and applications of nucleic acids. Specifically, this has included the formation of higher order DNA structures, such as those generated from two, three and four DNA strands, as well as those generated by the looping of DNA by restriction enzymes. I am also interested in the targeting of these complexes by small molecules, polyamides and other molecules.

Research projects

Modifying nucleic acid nanostructures by triplex formation (BBSRC). This research is focused on exploiting the construction of unorthodox DNA structures to the field of DNA nanotechnology (bionanotechnology), with the aim of bridging the gap between engineering and the life science interface.

Research group

Molecular and Cellular Biosciences

Research project(s)

Modifying nucleic acid nanostructures by triplex formation

We are exploiting the formation of DNA triplexes as a means for generating new DNA nanostructures.

DNA sequence recognition by triple helix formation

One means of achieving precise DNA sequence recognition over several base pairs involves the formation of intermolecular DNA triple helices.

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Articles

Book Chapters

Review

Undergraduate tutorials; molecular and cellular biochemistry.

Dr David Rusling
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
Southampton
SO17 1BJ

Room Number: 85/4041

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