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The University of Southampton
Biological Sciences

Dr Elizabeth Davies BSc(Hons), PhD

Research Fellow

Dr Elizabeth Davies's photo

Lizzie has worked as a Research Fellow at the University since 2014 and joined Biological Sciences in 2019.

I have a keen interest in the biology of lung diseases, particularly fibrosis and asthma.

My PhD studied the role of ADAM33, an asthma susceptibility gene hypothesised to involved in inflammation and remodelling of the airway using a transgenic mouse model. Alongside this, I studied an in vivo model of allergic asthma using IL-13 transgenic mice and identified that it could be used to model mechanisms of neutrophilic inflammation that are corticosteroid insensitive, a hallmark of severe asthma.

I have since switched focus to pulmonary fibrosis, working first within Clinical Experimental Sciences, and now closely alongside them while working for Dr Wang in Biological Sciences.

Research interests

Biology of lung disease.

Research group

Molecular and Cellular Biosciences

Research project(s)

Defining the role of zeb1-dependent epithelial-mesenchymal crosstalk in lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a life-threatening condition of the lungs where tissue becomes thickened, stiff, and scarred, limiting the amount of oxygen getting into the blood. The aim of this project is to provide effective targeted therapies for sufferers to reduce symptoms of this devastating disease and improve their quality of life as well as to identify biomarkers for IPF patients.

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Dr Elizabeth Davies
School of Biological Sciences
Faculty of Environmental and Life Sciences
Life Sciences Building 85
University of Southampton
Highfield Campus
SO17 1BJ
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