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The University of Southampton
Biomedical Imaging UnitEquipment and Facilities


Micro-Focused X-Ray Computed Tomography (μCT)

μCT is a non-destructive imaging technique that uses X-rays to generate high resolution 3D (volume) datasets from samples. Unlike a conventional clinical X-ray system, where image resolution is typically ranging between 0.25 -1.50 mm, this technique can offer spatial resolution up to 6 -8 μm. The scanner is comprised of an X-ray source, a rotation stage and an X-ray detector. To acquire a tomogram the specimen is mounted on to the rotation stage and is subsequently illuminated by X-rays during a foul 360o rotation. During this process thousands of radiographs are collected, which are then fed to specialized algorithms to reconstruct the volume image.

The scanner is designed as an imaging research tool for biology and medicine and is the first prototype machine of Nikon's new Med-X series. It was commissioned in August 2016 and is managed by the μ-VIS X-Ray Imaging Centre.
The BIU has a very strong collaboration with μ-VIS, based in Engineering on main Campus, which houses multiple complementary scanning systems supporting a wide range of sample sizes and types with imaged volumes up to 1.5 x 1 x 1m, and spatial resolutions down to approximately 200 nm.

The Med-X system is primarily dedicated to specific research projects but beam time may be available to other users by prior arrangement. Please contact Orestis Katsamenis in μ-VIS for further information.

Find out more about μCT imaging of soft tissues here.


Nikon Med-X Alpha MicroCT system
Nikon Med-X Alpha MicroCT system

Nikon Med-X Alpha (prototype)




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