lay-summaries-group-2017 | BRAIN UK | University of Southampton

Lay Summaries for all the studies supported by BRAIN UK within the past 12 months.

Please click on the link below to view the individual lay summary.

BRAIN UK Study Ref	Lay Summary	Project Status
23/007	A post-mortem study of progenitor cells and the injury response following severe traumatic brain injury	Active
23/008	Investigation of FGF receptor functions in human glioblastoma	Active
23/009	SPCA in ALS	Active
23/010	The role of amyloid-precursor protein processing (APP) in breast cancer; lessons learnt from Alzheimer’s disease	Active
23/011	Clinicopathological correlations of immune response in inflammatory neuropathies	Active
23/012	Expression of THIKl in temporal cortex from normal donors and those with Temporal Lobe Epilepsy (TLE)	Active
23/014	Delineating the neuropathophysiological mechanisms underpinning severe drug-resistant epilepsy in Alpers’ syndrome	Active
23/015	Epidemiologic, Histologic, and Molecular Features of Methylation Class Pleomorphic Xanthoastrocytoma	Active
23/016	Verifying the surrogate marker, NCOA2, for identifying the HEY1-NCOA2 fusion gene in mesenchymal chondrosarcoma (MCS)	Active
23/017	AN1792 immunotherapy effects on plaque-associated synapse loss and gliosis	Active
23/018	A Study of Tumours and Embryology of the Meninges and Skull (STEMS)	Active
23/019	Mass spectrometry mapping of childhood primary and recurrent cerebellar brain tumours	Active
23/020	Investigation the role of Cellular Prion protein (PrP C) in multi drug resistance (MDR) in schwannoma and meningioma tumours	Active
23/021	Expression of OxR1 in hypothalamus and pons from normal donors and those with Prader-Willi Syndrome (PWS	Active
23/022	Understanding Porphyromonas gingivalis Infection in Alzheimer’s Disease	Active
23/023	Understanding microenvironmental determinants of glioblastoma invasion	Active
23/024	The multifaceted role of MMPs and TIMPs in AD after immunotherapy	Active
23/025	Development of a mass-spectrometry tissue classifier for rapid diagnosis of brain tumours	Active
23/026	Genome and transcriptome analysis in DRPLA, other rare repeat expansion disorders and undiagnosed inherited ataxia tissue	Active
23/027	Molecular characterisation of novel and rare subtypes of high-grade glioma occurring in the paediatric and young adult age groups	Active
24/001	The mosaic brain: a new diagnostic approach in focal epilepsies	Active
24/002	Characterization of rare neuronal and glial tumour types to increase diagnostic accuracy, identify treatment targets and improve prognostication	Active
24/003	Investigation of corticogenesis defects in Dravet Syndrome patients	Active
24/004	P16 expression as a surrogate marker for homozygous deletion of CDKN2A in IDH-mutant astrocytomas	Active

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