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Centre for Human Development, Stem Cells and RegenerationOur news & events

HDH Lunchtime Seminar - Novel Models for Bone Regeneration and Dental Pulp Stem Cell Responses to Oxidative Stress

Published: 17 January 2013

Professor Alastair Sloan

Time: 13:00

Place: IDS Lecture Theatre, Level A, IDS Building

A free lunch is available from 12:30 in the Seminar Room, Level A IDS Building

Synopsis:


Professor Sloans’ research focusses on the biology of mineralised connective tissues, specifically focussing on their regenerative potential. He has a particular interest in the signalling processes that initiate and control the repair of the dentine pulp complex in teeth, and the effects of the application of members of the TGF-b family and isolated bioactive matrices from dentine and bone on pulpal cell behaviour.

He has developed fully characterised 3D organtypic culture systems for dental tissues and bone, providing innovative models for studying the biological behaviour of these tissues over extended periods of time. The functional behaviour of dental pulp stem cells (DPSCs) has also been studied, investigating how these cells may be manipulated to facilitate dentine and bone regeneration, as well as examining how their behaviour is altered during cell ageing.

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