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The University of Southampton
Chemistry

Ion conductance microscopy: from basics to advanced applications Seminar

Time:
15:00
Date:
25 March 2013
Venue:
Building 27, Room 2001 Chemistry Highfield University of Southampton SO17 1BJ

For more information regarding this seminar, please email Dr Andrew Hector at A.L.Hector@soton.ac.uk .

Event details

Part of the Electrochemistry Group Seminar Series

Scanning ion conductance microscopy (SICM) was invented by Paul Hansma at the University of Santa Barbara in 1989 (Hansma et al., 1989) and is a form of Scanning Probe Microscopy technique that uses glass pipette filled with electrolyte as an imaging probe to generate topographical images of surfaces. In 1997 SICM was modified and made applicable to nanoscale imaging of live biological cells by Yuri Korchev (Korchev et al., 1997;Korchev et al., 1997). Subsequent advances in SICM which include improved topographical resolution (Shevchuk et al., 2006) and the invention of “hopping probe ion conductance microscopy” (HPICM) (Novak et al., 2009) has brought the quality of SICM imaging to levels comparable with scanning electron microscopy whilst retaining live-cell imaging capabilities. Recently, we have solved the problem of measurement-independent probe-sample distance regulation, the vital missing component in scanning electrochemical microscopy (SECM) since its invention in 1989. This was achieved by combining SICM and SECM for simultaneous SICM-SECM imaging (Takahashi et al., 2010;Takahashi et al., 2011).

Speaker information

Dr Andrew Shevchuk, Ifls, University of Southampton. 2003 Ph.D. in Biophysics, Medical Physics and Bioengineering. “Design and development of scanning ion conductance microscope”. Faculty of Medicine, Imperial College London. 2000 M.Sc. in Computer Science. Department of specialized computer systems, Faculty of Applied Mathematics, Kiev Polytechnic Institute, National Technical University of Ukraine

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