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The University of Southampton

How Best Can Synthesis Support Bioactive Molecule Discovery? Seminar

4 June 2014
Building 27, Room 2001 Chemistry Highfield Southampton SO17 1BJ

For more information regarding this seminar, please email Dr Jon Watts at .

Event details

Prof Adam Nelson presents his seminar as part of the MDT seminar series

The discovery of bioactive small molecules is an enduring theme in medicinal chemistry and chemical biology. In this talk, three distinct approaches to the exploration of chemical space will be presented. First, an approach to the synthesis of natural product-like molecules with unprecedented scaffold diversity will be outlined. Second, an approach to the synthesis of lead-like molecular scaffolds will be described. Finally, a novel approach - which we have termed activity-directed synthesis - will be described in which the emergence of the synthetic route is guided solely by the bioactivity of the resulting products.

Speaker information

Prof Adam Nelson, University of Leeds. Professor of Chemical Biology

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