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The University of Southampton

Mass Spectrometry in Medicine Seminar

11 November 2015
Building 27, Room 2003 (L/R2), Highfield Campus, University of Southampton, SO17 1BJ

For more information regarding this seminar, please email John Langley at .

Event details

Professor Michael (Mike) Morris, Senior Director of Mass Spectrometry Reseqarch at Waters Corporation, Wilmslow presents a seminar as part of the Characterisation and Analytics Research Group's seminar series.

Mass spectrometry can be used for the determination and quantification of molecules. Chemicals can be specifically measured in the presence of many other compounds, and this makes the technique ideally suited for the determination of molecular biomarkers in physiological specimens.

This talk will focus on the basic principles of mass spectrometry, as well as the use of the analytical technique in a routine clinical environment for the quantification of drugs and metabolites, and the investigation of protein variants. Examples will be presented where mass spectrometry is now in routine use 

Future possibilities will also be examined where the technology may play a more direct role in clinical diagnostics during surgery.

Speaker information

Professor Michael (Mike) Morris, MS Research Group, Waters Corporation, Wilmslow & Department of Surgery and Cancer, Imperial College, London. Mike received his B.Sc. (Hons) in Analytical Chemistry from UMIST, Manchester in 1985, and a Ph.D. in mass spectrometry from the same institution in 1988 under the supervision of the late Professor Michael Barber FRS. He has been involved in a number of research projects, including the ion optic design of sector instruments, development of surface-induced dissociation and the application of tandem mass spectrometry. He spent time working in Japan (Osaka University), USA (Purdue University) and Canada (National Research Council) before joining Micromass/Waters in 1994. He founded the Clinical Operations Group in Waters in 1999, and was responsible for the development of applications of mass spectrometry in neonatal screening, therapeutic drug monitoring and clinical toxicology. This technology is now in wide use around the world for routine clinical chemistry analysis. Mike has been the co-organiser of a number of national and international meetings and authored more than 50 publications. He is also a Chartered Chemist and Fellow of the Royal Society of Chemistry (C.Chem., FRSC). He rejoined the mass spectrometry research team in 2010 and in 2012 he was appointed as a visiting Professor in the Department of Surgery and Cancer at Imperial College, London. Waters Corporation is a manufacturer of analytical equipment, of which the Wilmslow facility is the mass spectrometry Centre of Excellence. There are four major manufacturers of mass spectrometers in the world, and the Manchester area has been (and still is) probably THE major centre for this analytical technique.

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