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The University of Southampton
Chemistry

Molecular Machines Double Bill Seminar

Time:
13:00 - 14:00
Date:
8 October 2019
Venue:
27/2001

For more information regarding this seminar, please email Prof. Steve Goldup at S.Goldup@soton.ac.uk .

Event details

We have two visiting speakers from Japan who are part of a large project on the development and analysis of molecular machines.

The steps toward synthetic molecular engines: Design of multiblock amphiphiles mimicking transmembrane proteins

Prof. Kazushi Kinbara (Tokyo Institute of Technology)

We have been involved in development of stimuli-responsive molecules inspired by biological molecular machineries.  The initial approach started form ferrocene-based molecules which undergo rotary motions in response to stimuli in organic solvents.  A recent approach focuses on amphiphilic molecules working in lipid bilayers which allow use of various stimuli as input energies.  The design strategies and properties of these molecules will be featured.

Watching dynamic motions of protein motors with plasmonic nanoprobes

Ryota Iino (Institute for Molecular Science)

We are developing high-precision and high-speed single-molecule imaging methods visualizing fast and free motions of individual protein motors at work with angstrom localization precision and microsecond time resolution. I will discuss chemo-mechanical coupling mechanisms and coordination mechanisms of linear motors kinesin, dynein, and processive chitinase, and a rotary motor V1-ATPase revealed by our techniques.

For more information on Molecular machines.

Speaker information

Prof Kazushi Kinbara, Tokyo Institute of Technology, Japan. Their expertise spans membrane supramolecular chemistry and synthetic molecular machines through to the analysis and measurement of the behaviour of natural molecular machines such as kinesis and ATPase.

Prof. Ryota Iino, Institute for Molecular Science, Japan. Their expertise spans membrane supramolecular chemistry and synthetic molecular machines through to the analysis and measurement of the behaviour of natural molecular machines such as kinesis and ATPase.

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