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The University of Southampton
Courses

BIOL6038 Immunology

Module Overview

This module covers the major topics in cellular and molecular immunology, including antigen recognition, antigen processing and presentation to B and T cells, the molecular events leading to the generation of antibody and T cell receptor diversity, antibody effector functions, the role of CD4 and CD8 T cell subsets and NK cells in immune responses, self-tolerance and autoimmunity, the inflammatory response and the role of immunity in protection against pathogens and cancer. The module will allow core immunological principles to be utilised in developing research proposals.

Aims and Objectives

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Know the cellular ontogeny and organ involvement in immunity
  • Explain the principles of self-tolerance and autoimmunity
  • Know how the immune system can fight infections and cancer, including examples of immunotherapy to harness host immunity
  • Know how to engage with current research in immunology and translational immunology
  • Know the difference between innate and adaptive immunity
  • Understand what antigens are and how they are presented.
  • Understand the role of NK cells in innate and adaptive immunity
  • Know the maturation steps of T and B cells and how they work
  • Understand how cytotoxic T cells kill and the role of helper T cells
  • Understand cytokine biology and how the cytokine network interferes with the immune system
  • Understand the mechanisms involved in control of immune responses
  • Describe the cellular and molecular basis of the inflammatory response

Syllabus

The module will cover the major topics in cellular and molecular immunology, including antigen recognition, antigen processing and presentation to B and T cells, the molecular events leading to the generation of antibody and T cell receptor diversity, antibody effector functions, the role of CD4 and CD8 T cell subsets and NK cells in immune responses, self-tolerance and autoimmunity, the inflammatory response and the role of immunity in protection against pathogens and cancer.

Learning and Teaching

Teaching and learning methods

Teaching will be a mixture of formal lectures (11 sessions) and small group tutorials (1-2 sessions). Independent study is also expected as part of this module. Consultation with course tutors to develop research proposals is encouraged.

TypeHours
Independent Study126
Lecture24
Total study time150

Assessment

Summative

MethodPercentage contribution
Research proposal 25%
Written exam  (2 hours) 75%

Referral

MethodPercentage contribution
Research proposal 25%
Written exam  (2 hours) 75%

Repeat Information

Repeat type: Internal & External

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