The University of Southampton
Courses

BIOL6045 Neurodegenerative Disease

Module Overview

This module describes the neurobiology that underpins the aetiology and pathogenesis of neurodegenerative disease that has been a focus of intense and exciting research activity over the last several decades. The course is largely a research-led unit whereby the contributing staff will where possible, lecture on topics that are their own research interests.

Aims and Objectives

Module Aims

1. To explore the various mechanisms that neurones employ to execute cell death processes in both normal and abnormal conditions. 2. To improve your understanding of the pathogenic mechanisms that cause cell death in several neurodegenerative diseases. 3. To be able to evaluate examples of current research in this field undertaken both in Southampton and elsewhere.

Learning Outcomes

Learning Outcomes

Having successfully completed this module you will be able to:

  • Be aware of the various means by which neurones respond to stressful situations and execute homeostatic and neuronal death processes.
  • Be aware of the pathological hallmarks that characterise the common neurodegenerative diseases.
  • Demonstrate a basic understanding of the molecular and cellular mechanisms that are believed to underlie many of these neurodegenerative diseases.
  • Be able to use this understanding to predict avenues of therapeutic intervention.
  • Discuss current research in this field and how it promotes further understanding of the underlying pathogeneses of diseases covered.

Syllabus

The neurobiology that underpins the aetiology and pathogenesis of neurodegenerative disease has been a focus of intense and exciting research activity over the last several decades. The course is largely a research-led unit whereby the contributing staff will where possible, lecture on topics that are their own research interests.

Learning and Teaching

Teaching and learning methods

Formal lectures, research-led seminars, poster session and independent study of selected reference materials

TypeHours
Independent Study126
Lecture24
Total study time150

Assessment

Assessment Strategy

The module is assessed by written examination at the end of semester comprising one 2-hour paper requiring two questions to be answered from a choice of three, one of which is an either/or pair (65% of total module mark) And Separate oral presentation in which the student will be required to present the salient findings from a self-selected primary publication to two academics. This will be followed by a short question and answer session (15% of total module mark). The student will be required to submit a written evaluation (

Summative

MethodPercentage contribution
Literature review with presentation  (1000 words) 35%
Written exam  (2 hours) 65%

Referral

MethodPercentage contribution
Literature review with presentation  (1000 words) 35%
Written exam  (2 hours) 65%
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