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The University of Southampton
Cancer Research UK Centre

Southampton's designated Cancer Research UK Centre 

The CRUK Centre at Southampton brings together laboratory teams concentrated on immunology and lymphoid biology with a broad mission to translate discoveries into treatment across a range of tumour types. It is supported by a dynamic patient involvement group.

Long-standing expertise in antibody therapeutics, fundamental understanding of adaptive immunity and the behaviour of cancer microenvironments have given rise to a rich translational pipeline of phenotypic analysis and new reagents.

This feeds into a clinical environment that delivers the highest quality care, including one of the largest departments of academic cancer surgery and one of the most research-active oncology centres in the country.


The Centre is a partnership between Cancer Research UK, the University of Southampton and University Hospitals Southampton NHS Trust

The main themes of research in the Centre are:

  • Antibody therapy for Cancer using antibodies to target cancer cells and the switches of the immune system
  • Antigen Processing and Immunomodulation: finding out how the immune system recognises cancer cells, and ways to make them more visible
  • The Tumour Microenvironment: understanding how the inflammatory cells in cancers drive their growth and survival, and how to target this for treatment
  • Lymphoid Malignancy: how cancers of the lymphatic system develop and can be treated
  • Healthcare Data and Molecular Phenotyping: how we combine the molecular information about cancers with the results of our tests and treatment, to help future patients make the best choices.

The Centre hosts doctoral training schemes for PhD students wishing to work with the groups of the Centre, and for Clinical Research Fellows wishing to complete a higher degree.

For any enquiries please contact the Centre Manager:

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