The University of Southampton
Engineering

Research project: 3D printing of PEEK and HA/beta-TCP tissue engineering (TE) scaffolds

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This project has been built on established relationships between the University of Southampton's Faculties of Engineering and the Environment and the industrial partner, Invibio, who is the sponsor of this studentship. 

Project Overview

Invibio is the market leader in providing PEEK-based biomaterial solutions to medical device manufacturers around the world.  The aim of the project is to design and set up a device process suitable for extrusion freeform fabrication of PEEK and  HA/beta-TCP tissue engineering scaffold for health care application, to investigate the effect of process parameters on microstructure and biocompatibility of the scaffold, and to characterize the scaffold and composite using X-CT, TGA, DSC and SEM.

Project objectives:

  1. To design and set up a device suitable for high temperature extrusion of PEEK
  2. To fabricate beta TCP (and/or HA, bioglass) tissue engineering scaffolds using the powder extrusion with pores of circa 600-1000 microns.
  3. To overmould the scaffolds or cover with powder/melt to creat a PEEK shape with an internal interconnected network.
  4. To investigate the effect of process parameters on microstructure and biocompatibility of PEEK scaffolds, to characterize the PEEK scaffold and ceramic/PEEK composite using X-CT, TGA, DSC and SEM, to investigate the in vitro performance of the fabricated scaffolds

Staff

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