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The University of Southampton

Research project: Development of a new knee replacement - Dormant - Dormant

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Each year an estimated 1,324,000 artificial knee joints (total knee replacements – TKR) are implanted worldwide. Underlying computer based research performed by the Bioengineering Sciences Research Group has played a central role during the development of a new design of TKR for DePuy-Synthes, a major orthopaedic manufacturer. The design programme, the biggest in DePuy's history, had a budget in excess of $10 M and aimed to replace the existing TKR system.

As part of a University Technology Partnership with the Bioengineering Sciences Research Group, DePuy adopted computational techniques developed within the group as screening tools to (i) assess polyethylene wear due to repeated use of the implant and (ii) account for the effects of surgical variability on the performance of the implant, during the early design phases of its newest knee replacement. The research allowed DePuy to choose the most robust solution when proceeding to mechanical testing and saved years in the design cycle. The patient will benefit too by receiving an implant that is more robust and able to withstand the rigours of use.

Associated research themes

Bioengineering and human factors

Related research groups

Bioengineering Science

Key Publications

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