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The University of Southampton

Research project: Simulation of tissue differentiation in uncemented hip implants based on a mechanoregulatory hypothesis

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Uncemented hip replacement depends upon achieving a good interlock with the supporting bone tissue. In this study, numerical methods were used to explore the interface between uncemented implants and surrounding bone.

Project Overview

A novel algorithm was developed to simulate tissue differentiation around the implant using finite element methods, to study implant design features that might promote bone formation at the interface. A series of case studies were used to focus on porous coating and implant geometries. The results were compared to clinical data for corroboration. The results obtained corroborated well with clinical data and clearly demonstrated the efficacy of the algorithm in simulating tissue differentiation around uncemented implants, as well as highlighting the importance of design features in promoting bone ingrowth and stable fixation.

Simulation of tissue
Simulation of tissue

Related research groups

Bioengineering Science
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