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The University of Southampton
Wessex Imprinting GroupInformation for patients

Prader-Willi Syndrome

The main features of Prader-Willi syndrome are:

Genetic causes

80% of people with PWS have a deletion of chromosome 15 (a spontaneous deletion on the chromosome from the father). The other main cause is maternal UPD of chromosome 15. Rarer causes include imprinting problems on chromosome 15.

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