Skip to main navigationSkip to main content
The University of Southampton
Growth Hormone 2004 Project

Cross-sectional study

The aim of this study was to collect blood samples from a large number of elite athletes from differing ethnic groups and different sports in order to establish physiological reference ranges of IGF-I and P-III-NP amongst elite athletes. This information was used to help determine the decision limits used in the final anti-doping strategy.

Elite athletes were invited from any ethnic group. A wide range of sports were covered internationally.

This study is now complete and the results from this study have been published in Clinical Endocrinology in 2009 (1).

We also examined marker concentrations in adolescent athletes in order to determine whether changes in the application of the test were need in athletes aged under 18 years. This study is now complete and the results from this study have been published in the Journal of Clinical Endocrinology & Metabolism (2).


(1) Erotokritou-Mulligan I, Bassett EE, Cowan DA, Bartlett C, McHugh C, Sonksen PH, Holt RI. Influence of ethnicity on IGF-I and procollagen III peptide (P-III-P) in elite athletes and its effect on the ability to detect GH abuse. Clin Endocrinol (Oxf) 2009 January;70(1):161-8.

(2) Guha N, Erotokritou-Mulligan I, Burford C, Strobridge G, Brigg J, Drake T, Bassett EE, Cowan D, Bartlett C, Sonksen PH, Holt RI. Serum insulin-like growth factor-I and pro-collagen type III N-terminal peptide in adolescent elite athletes: implications for the detection of growth hormone abuse in sport. J Clin Endocrinol Metab 2010 June;95(6):2969-76.

Privacy Settings