The GH-2004 project

Project description

This project was a continuation of the GH-2000 project undertaking the additional validation work required prior to having the test implemented by WADA.

The specific aims of the GH-2004 project were:

• To validate a test for growth hormone misuse based on the measurement of two bio-markers IGF-I and P-III-NP
• To develop a reference range for two growth hormone sensitive markers (IGF-I and P-III-P) in elite athletes
• To study the variability in these markers over time
• To investigate the sensitivity of these markers to growth hormone administration in different ethnic groups
• To investigate the effects of injury on the growth hormone sensitive markers in different ethnic groups

The GH-2004 Project Components:

i). Cross-sectional study

ii). Double-blind study

iii). Longitudinal study

iv). Injury study

v). Pre-analytical storage conditions