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Research project: Adventitious lung sounds as indicators of severity and recovery of lung pathology and sputum location

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This project is an important step in our long-term goal of developing a new, objective and reliable outcome measure based on lung sounds to assess patients’ response to respiratory interventions. This is needed as there is a significant lack of evidence regarding the effectiveness of current respiratory treatments. We propose that changes in adventitious lung sounds (ALS) have the potential to contribute to the development of the respiratory evidence-base practice allowing assessment and monitoring of patients, even in populations that are unable to collaborate with the measurements. In order to reach this goal, it is critical to undertake validation studies such as that proposed here to ensure that the lung sounds are responsive to change of the magnitude of those produced during respiratory treatments

This project aims to assess if added lung sounds are responsive to change (treatment) and can be used as an outcome measure, enabling professionals to monitor patients and assess the effectiveness of respiratory treatments. To validate the responses to treatment given by the acoustic of the lungs, chest imaging will have to be included. A pilot study will be conducted to maximise safety and effectiveness of the study and train the research team. The main study will then be implemented and analysed followed by a professional dissemination. The plan is to recruit 100 patients with Lower Respiratory Tract Infection, who attend to casualty of the Hospital Infante D. Pedro. Patients’ demographic and anthropometric, lung sounds, lung function, breathlessness, oxygen saturation and chest CT scan will be collected within 24h of their first appointment. Patients’ will then be treated with daily medication and with respiratory physiotherapy 3 times a week during 2 weeks. After this period of time, the same measurements will be repeated

Project team

Bruton A, Barney A

Project funder

Fundação para a Ciência e Tecnologia (FCT)

Associated research themes

Respiratory System

Related research groups

Active Living and Rehabilitation
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