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The University of Southampton
IBD Southampton research study

Publications

Ashton JJ, Beattie RM (2019) Letter to the Editor: Treatment of active crohn's disease with an ordinary food-based diet that replicates exclusive enteral nutrition. Gastroenterology 

Mossotto E, Ashton JJ, O’Gorman L, Pengelly RJ, Beattie RM, MacArthur BD, Ennis S (2019)  GenePY – a score for estimating gene pathogenicity in individuals using next-generation sequencing data. BMC Bioinformatics 20(1):254.

Ashton JJ, Beattie RM (2019) Comment: Personalised therapy for inflammatory bowel disease:fiction or reality. Lancet 393(10182):1672-1674.

Ashton JJ, Mossotto E, Ennis S, Beattie RM (2019) Personalising medicine in inflammatory bowel disease-current and future perspectives. 8(1):56-69.

Ashton JJ, Borca F, Mossotto E, Coelhi T, Batra A, Afzal NA, Phan HTT, Stanton M, Ennis S, Beattie RM (2019)  Increased prevalence of anti-TNF therapy in paediatric inflammatory bowel disease is associated with a decline in surgical resections during childhood. Alimentary Pharmacology & Therapeutics 49(4):398-407.

Ashton JJ, Borca F, Mossotto E, Phan HTT, Ennis S, Beattie RM (201)  Analysis and hierarchical clustering of blood results prior to diagnosis in paediatric inflammatory bowel disease. Inflammatory Bowel Diseases 

Ashton JJ, Batra A, Beattie RM (2018) Paediatric inflammatory bowel disease - brief update on current practice. Paediatrics and Child Health 28(11):507-514.

Ashton JJ, Beattie RM (2018) Faecal calprotectin; what does this mean for the paediatric inflammatory bowel disease phenotype? JPGN  66(4):e115.

Ashton JJ. Beattie RM. (2018) Gastro-oesphageal reflux in infants; what are we treating? Lancet Child and Adolescent Health 2(7):475-476.

Ashton JJ, Bonduelle Q, Mossotto E, Coelho T, Batra A, Afzal NA, Vadgama B, Ennis S, Beattie RM. (2018) Endoscopic and histological assessment of paediatric inflammatory bowel disease over a three year follow-up period. Journal of Pediatric Gastroenterology & Nutrition 66(3):402-409

Ashton JJ, Cullen M, Afzal NA, Coelho T, Batra A, Beattie RM (2018) Is the incidence of paediatric inflammatory bowel disease still increasing? Arch Dis Child 103(11):1093-1094.

Ashton JJ, Harnden A, Beattie RM. (2018) Paediatric inflammatory bowel disease – improving early diagnosis. Arch Dis Child 103(4):307-308.

Gavin J, Ashton JJ, Heather N, Marino LV, Beattie RM. (2018) Nutritional support in paediatric Chrohn’s disease: outcome at 12 months. Acta Paediatr 107(1):156-162.

Gavin J, Marino LV, Ashton J, Beattie RM. (2018)  Patient, parent and professional perception of the use of maintenance enteral nutrition in paediatric Crohn’s disease. Acta paediatr 107(12):2199-2206.

Ashton JJ, Colquhoun CM, Cleary DW, Coelho T, Haggarty R, Mulder I, Batra A, Afzal NA, Beattie RM, Scott KP, Ennis S. (2017) 16S sequencing and functional analysis of the fecal microbiome during treatment of newly diagnosed pediatric inflammatory bowel disease. Medicine (Baltimore) 96(26):e7347.

Mossotto E, Ashton JJ, Coelho T, Beattie RM, MacArthur BD, Ennis S. (2017) Classification of paediatric inflammatory bowel disease using machine learning. Scientific Reports 7(1): 2427.

Andreoletti G, Shakhnovich V, Cristenson K, Coelho T, Haggarty R, Afzal NA, Batra A, Petersen B-S, Mort M, Beatie RM, Ennis S. (2017) Exome analysis of rare and common variants within the NOD signaling pathway. Nature Scientific Reports 7 (ePrint ID: 406935)

Takahashi S, Andreoletti G, Chen R, Munehira Y, Batra A, Afzal NA, Beattie RM, Bernstein A, Ennis S, Snyder M. (2017) De novo and rare mutations in the HSPA1L heat shock gene associated with inflammatory bowel disease. Genome Medicine 9(1):8. (ePrint ID: 404884)

Ashton J, Beattie R, Ennis S, Cleary D (2016) Analysis and interpretation of the human microbiome. Inflamm Bowel Dis 22(7):1713-22. (ePrint ID: 396239)

Ashton J, Coelho T, Ennis S, Vadgama B, Batra A, Afzal N, Beattie R (2016) Endoscopic versus histological disease extend at presentation of paediatric inflammatory bowel disease. J PediatrGastroenterolNutr 62(2):246-51. (ePrint ID: 383871)

Ashton JJ, Coelho T, Ennis S, Batra A, Afzal NA, Beattie RM (2016). Endoscopic versus Histological disease extent at Presentation of Paediatric Inflammatory Bowel Disease (PIBD) Journal paediatric gastroenterology and nutrition. 62(2):1229-36. (ePrint ID: 383871)

JJ Ashton, Hendt P Versteegh, Akshay Batra, Nadeem A Afzal, Andrew King, DM Griffiths, RM Beattie and MP Stanton (2016). Colectomy in Paediatric Ulcerative Colitis; a Single Centre Experience of Indications, Outcomes and Complications. Journal Pediatric Surgery. 51(2):277-81.

Andreoletti G, Ashton JJ, Coelho T, Willis C, Haggarty R, Gibson J, Holloway J, Batra A, Afzal NA, Beattie RM, Ennis S (2015). Exome analysis of patients with concurrent pediatric inflammatory bowel disease and autoimmune disease. Inflamm Bowel Dis.;21(6):1229-36.

Ashton J, Coelho T, Ennis S, Batra A, Afzal N, Beattie R (2015) Presenting phenotype of paediatric inflammatory bowel disease (PIBD) in Wessex, Southern England 2010-13. ActaPaediatr 104(8):831-7. (ePrint ID: 376405)

Ashton JJ, Coelho T, Ennis S, Batra A, Afzal NA, Beattie RM (2015). G355 Presenting phenotype of ulcerative colitis (UC) in children 2010-13. Archives of Disease in Childhood; 100(Suppl 3):A145-A146.

Ashton JJ, Coelho T, Ennis S, Batra A, Afzal NA, Beattie RM (2015). G371(P) Presenting phenotype of crohn's disease (cd) in children 2010-13. Archives of Disease in Childhood; 100(Suppl 3):A152-A152.

Ashton JJ, Wiskin AE, Ennis S, Batra A, Afzal NA, Beattie RM (2014). Rising incidence of paediatric inflammatory bowel disease (PIBD) in Wessex, Southern England. Arch Dis Child.

 

Coelho T, Andreoletti G, Ashton J, Pengelly R, Gao Y, RamaKrishnan A, Batra A, Beattie R, Williams A, Ennis S (2014) Immuno-genomic profiling of patients with inflammatory bowel disease: a systematic review of genetic and functional in vivo studies of implicated genes. Inflamm Bowel Dis 20 (10). (ePrint ID: 368515)

 

Christodoulou K, Wiskin A, Gibson J, Tapper W, Willis C, Afzal N, Upstill-Goddard R, Holloway J, Simpson M, Beattie R, Collins A, Ennis S (2013) Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes. Gut 62 (7):977-984 [Selected for F1000Prime following F1000 recommendation for being of special significance in its field] (ePrint ID: 337649)

 

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