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The University of Southampton
Institute for Life Sciences

Bioengineering Sciences Seminar Series Event

13:00 - 14:00
10 February 2012
Room 2207, Life Sciences Building (85)

For more information regarding this event, please telephone Dr Nick Evans on 023 8077 7222 Ext 3293 or email .

Event details

Electron Microscopy of Nanomaterial-tissue Interfaces, Dr Alexandra Porter, Department of Materials, Imperial College London.

Following the huge growth in nanotechnology-related industries, significant concerns have arisen about their impact on both human health and the environment. Carbon nanotubes and silver nanostructures are amongst the most commercially relevant class of nanomaterial, with annual production capacities in thousands of tonnes. Despite great enthusiasm for the engineering applications of these classes of nanomaterial, recent studies have raised concerns about their potential health and environmental impact. There have been many reports on the toxicity of carbon and silver nanomaterials, however the data provided in these reports are inconclusive as there is little consistency between the toxicity assays being conducted or the physicochemical format of the nanomaterials being tested.

This talk will describe studies being performed in our laboratory to develop a mechanistic understanding of how the physicochemical properties (i.e. aggregation state, surface characteristics and length) of engineered nanomaterials relate to their interaction with cells and proteins, both in situ and in vivo. The application of state-of-the art high resolution and analytical electron microscopy methods to characterise interfaces between the biological milieu and synthetic materials will also be discussed.

Speaker information

Dr Alexandra Porter,Senior Lecturer in the Department of Materials, Imperial College London.

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