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The University of Southampton
Institute for Life Sciences

Bioengineering Seminar Series Event

Time:
13:00 - 14:00
Date:
12 April 2013
Venue:
Room 2207, Life Sciences Building (85), Highfield Campus, University of Southampton, University Road, SO17 1BJ

For more information regarding this event, please email Dr Nick Evans at N.D.Evans@soton.ac.uk .

Event details

In-vivo spectroscopy of oscillating blood vessels and tissue health

ABSTRACT
Increasingly we are monitoring the distribution of oxygen through the microcirculation using optical techniques such as optical reflectance spectroscopy, near infrared spectroscopy and laser Doppler fluximetry. Mean blood oxygen saturation and tissue oxygen index derived by optical and near infrared spectroscopy respectively evoke a concept that we can measure oxygen delivery to the tissue. Laser Doppler fluximetry provides us with a measure of the concentration of moving red blood cells in the skin. This talk will describe how we can use these non-invasive techniques to improve our understanding of the complex dynamic mechanisms that match oxygen supply with oxygen demand. Intrinsic oscillations in blood vessels known as vasomotion have been observed for over 150 years but their role in optimising the haemodynamics of the cardiovascular system is poorly understood. The structure of the blood vessel wall predisposes the regulation of vasomotion to be of neurogenic, myogenic or endothelial origin. Spectroscopic research is now beginning to identify these mechanisms and their function in maintaining tissue health.

Speaker information

Dr Claire Thorn,University of Exeter,Research Fellow, Diabetes and Vascular Medicine

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