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The University of Southampton
Institute for Life Sciences

'Not a little square', an invited seminar presentation Event

12:00 - 13:00
20 November 2015
University of Southampton, Lanchester Building (7), Room 3023, Highfield Campus, Southampton, SO17 1BJ

For more information regarding this event, please telephone Dr Nick Evans on +44 (0)23 8120 3293 or email .

Event details

Digital imaging is used increasingly as part of the standard toolchain employed to test scientific hypotheses. Dr Michael Doube's research domain is skeletal biology; and in particular the responses of tendon, bone and cartilage to mechanical load.

Speaker information

Dr Michael Doube,Royal Vetinary College, London,In my work I have used a number of methods, from confocal and scanning electron microscopy to X-ray microtomography (XMT) and nanoindentation. Correlative imaging, where different modalities are applied to the same specimen space, can reveal important dynamic phenomena by combining measurement dimensions. Key to unlocking meaning from digital images is careful implementation and application of software tools. For skeletal work I have developed the easy-to-use ImageJ plugin BoneJ which is available online for free with open source code. Recently, I have demonstrated the use of iodine vapour as a useful staining technique for XMT of insects, shown that structure model index does not work, and introduced an ellipsoid-fitting model for measuring rods and plates in trabecular bone.

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