Skip to main navigationSkip to main content
The University of Southampton
Institute for Life Sciences

Zepler Institute Seminar Event

Dr Jonathan West
Time:
12:30 - 13:30
Date:
7 December 2015
Venue:
B53 4025A/B

For more information regarding this event, please email Ruth Churchill at R.Churchill@soton.ac.uk .

Event details

Microfluidic Single Cell Analytics

 

Abstract:

As microfluidic dimensions approach the length scale of a single cell, flow becomes laminar and manipulations become deterministic to enable exquisite spatial and temporal control. This quality can be used to provide superior assay resolution and also to address previously intractable questions in cell biology. Using examples from my research, I will show how microfabricated platforms afford the spatial precision to investigate neuronal and tumour systems, and then extend this principle to resolving cellular dynamics with millisecond resolution. The presentation will conclude with a discussion on the importance of high throughput single cell analysis for understanding heterogeneity in cellular populations. This research involves the use of droplet microfluidics and microwell array principles to measure variations in gene expression and communication that drive tumour evolution and underpin stem cell differentiation.

 

Biography:

Jonathan West MRSC is an Institute for Life Sciences Research Lecturer with 18 years’ experience from PhD (“microsystems for genetic diagnostics”) to present working at the interface between microtechnology and biomedicine. This included threes years industrial micro/nanotechnology commercialisation experience. In the last seven years, Jonathan has been developing microfluidic platforms for high throughput single cell biology. He has five patents, 32 peer-reviewed publications (>1700 citations; h-index 18), as well as two book chapters.

University website: https://www.southampton.ac.uk/medicine/about/staff/jjw1a11.page

Personal website: http://www.personal.soton.ac.uk/jjw1a11/Jonathan_West_Home.html

 

Useful Downloads

Need the software?PDF Reader

Speaker information

Dr Jonathan West,Institute for Life Sciences Research Fellow

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×