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The University of Southampton
Institute for Life Sciences

Seminar: Transcatheter replacement heart valves Event

Heart Valves
15:00 - 16:00
5 April 2016
University of Southampton, The Lanchester Building (7), Room 3019, Highfield Campus.

For more information regarding this event, please email Dr Nick Evans at .

Event details

We are pleased to welcome Dr Deon Bezuidenhout from the Chris Barnard Division of Cardiothoracic Surgery, a materials scientist developing transcatheter replacement heart valves. Deon is the co-founder of a company manufacturing these devices (

Speaker information

Dr Deon Bezuidenhout,University of Capetown, South Africa,Two types of valves have been used as surgical replacements for more than half a century. Mechanical valves are very durable but require closely monitored, lifelong anticoagulation. In contrast, bioprosthetic (BP) valves made from treated animal tissue do not require long-term anticoagulation, but have limited durability. The more recent advent of transcatheter aortic valve implantation (TAVI) provides an additional solution for elderly first world patients who are unable to withstand the trauma of open-heart surgery. For every patient who receives a heart valve in these nations there are, however, 50-100 young patients in developing countries who need replacement of valves due to rheumatic heart disease (RHD), but have no access to cardiac surgery. Heart valves that do not require lifelong anticoagulation, are affordable, durable in young patients, suitable to RHD pathologies and implantable in secondary hospitals via minimally invasive techniques, are thus proposed and described.

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