Research interests
Imaging the lung. Imaging of inhaled, radiolabelled compounds with gamma scintigraphy including Single Photon Emission Computed Tomography (SPECT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET) and computed tomography (CT) for both two and three-dimensional scintigraphy of inhaled agents.
Mathematical modelling of inhaled particles via well established collaborations with Prof John Fleming, Southampton General Hospital and Dr Ted Martonen of the US Environmental Protection Agency, N Carolina, US.
The use of lung imaging techniques for translational medicine. Exploring the use of techniques such as SPECT, CT and 3-D ventilation imaging as tools for improving the diagnosis and treatment of respiratory disease. Funded as part of the NIHR Southampton Respiratory Biomedical Research Unit (BRU). The Imaging group is one of 5 programmes of research within the BRU. Funding is for 4 years form April 2008.
http://www.som.soton.ac.uk/research/iir/About_IIR/bru/
The measurement of muco-ciliary clearance in cystic fibrosis using two and three-dimensional imaging techniques, working with Prof Eric Alton and Dr Jane Davies of Imperial College and the UK Cystic Fibrosis Gene Therapy Consortium, funded by the Cystic Fibrosis Research Trust.
http://www.cfgenetherapy.org.uk/
The measurement of epithelial permeability in the lungs using an inhaled radiolabels technique.
The mapping of deposition of inhaled particles in the lungs of asthmatics and healthy volunteers, working with Air Liquide (France)
The use of inhaled, unfractionated heparin as a mucolytic in hyper-secretory lung disease and the formulation of active agents for inhalation. Collaborating with Dr Jan Shute, Reader in Pharmacology, School of Pharmacy, University of Portsmouth.
In vitro assessment of aerosols
The Southampton Imaging Group
The Imaging Group is lead jointly by Dr Joy Conway (School of Health Sciences) and Prof John Fleming (Southampton University Hospitals Trust). The Aerosol Group is a cross-disciplinary research group, specialising in the application of its expertise in particle science and imaging technology.
Professor Joy Conway
Lead
Prof John Fleming
Joint Lead
Consultant Physicist, Nuclear Medicine, Southampton General Hospital
Members
Dr Livia Bolt, Physicist
Nuclear Medicine radiography Team, lead by Sandra Johns and Nick Bryant.
CT Radiography Team, lead by Kate Walker
Dr Charles Peebles, Consultant Radiologist
Dr Mary Carroll, Consultant Respiratory Physician and Director of Adult Cystic Fibrosis Services
Dr Gary Connett, Consultant Paediatric Physician and Director f Paediatric Cystic Fibrosis services
Jackie Hunt, Research Administrator
Dr Peter Howarth, Reader in Respiratory Medicine
Dr Lesley Collier, Lecturer in Occupational Therapy and Research Fellow
Lesley-Ann Castle and Emma Francis, BRU Research Nurses
Dr Michael Bennett, BRU Senior Clinical Scientist
Dr Patrick Dennison, BRU Clinical Research Fellow
Dr Tom Havelock, BRU Clinical Research Fellow
Past Projects
2000-2003
A project funded by the Wellcome Trust explored novel approaches to the delivery of technetium complexes to the lung surface.
2000-2004
An EPSRC funded joint collaboration investigated technology platforms for the delivery of dry powders for inhalation. This was a collaboration with the University of Bath (Dr Rob Price, Dept of Pharmacy and Phamaceutics), Loughborough University (Prof Peter Smith and Dr Paul Conway, Dept of Engineering and Prof Ron Summers, Dept of Information Technology), Vectura Ltd , CSW Ltd, Bespak plc.
2000 to date
Several collaborations with industry on a variety of projects including: Astra Zeneca (Sweden), 3M, Pharmagene, Britannia Pharmaceuticals Ltd and Air Liquide (France)
Research group
Active Living and Rehabilitation
