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The University of Southampton
Interdisciplinary Research Excellence

Death and rise of introns Event

11 July 2013
IDS lecture theatre, level A, Southampton General Hospital

For more information regarding this event, please email Robert Murray at .

Event details

Dr Igor Vorechovsky, Principal Research Fellow, University of Southampton


Most of our genes are ‘in pieces': protein-coding regions are interrupted by intervening sequences or introns that need to be removed to ensure accurate gene expression. Previously regarded as ‘junk DNA', it is now clear that introns and their removal by the largest cellular machinery provide amazing opportunities for gene expression control.

Introns also significantly contribute to evolution, speciation, phenotypic variability and genetic disease, including cancer. Better understanding of functional consequences of natural intronic variability will be important for successful disease interventions and personalized medicine of the future.

A free LUNCH is available from 12.30 in the seminar room opposite

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