Quantitative proteomic profiling of primary cancer-associated fibroblasts in oesophageal adenocarcinoma
British Journal of Cancer publication
Dr Spiros D. Garbis and Prof Timothy Underwood co-led this study, which provides novel biological insight to how Cancer Associated Fibroblasts (CAF), a basic component of the tumour microenvironment, promotes cancer cell aggressiveness of the oesophagus. Also, this study has revealed alternative treatment approaches of oesophageal cancer through the targeting of CAF expression.
The article can be retrieved in the following link:
https://www.nature.com/articles/s41416-018-0042-9