S3RI Seminar - Statistics for Biological Networks, Ernst Wit (University of Groningen) Seminar

Event details

Learning biological networks from data is not as straightforward as it may seem. The whole concept of network inference in genomics has multiple meanings and interpretations. It can refer to “causal” or “topological” considerations, i.e., learning about functional relationships in the genomic system or to considerations about the structure of the overall genomic network. Moreover,the genomic network does not really exists and can simultaneously refer to gene regulatory networks, cell signalling networks, metabolic networks etc. In this talk I aim to motivate a hierarchy of network inference strategies, starting at the single cell level and finishing at global structural network inference. It will involve stochastic and ordinary differential equation models, graphical modelling and random graph modelling.