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The University of Southampton

Dr Ahmed Alhendi BSc, MSc, PhD

Research Fellow in Bioinformatics

Dr Ahmed Alhendi's photo

Dr Ahmed Alhendi is a Research Fellow in Bioinformatics within the Faculty of Medicine at the University of Southampton.

Dr Alhendi a biomedical scientist with 6 years’ work experience in Bioinformatics and computational methods. His expertise lies in bioinformatics analysis, integration, and interpretation of genomic and clinical datasets, developing computational methods to answer fundamental questions in cancer and rare disease. He is proficient in planning, designing and executing data-driven experiments.

He completed his PhD in Genetics at the department of Genetics at the University of Leicester, investigating genetic and transcriptomic changes associated with alternative lengthening of telomeres in Sarcoma cell lines. Subsequently, he worked in Nicola's Royle's laboratory at the University of Leicester, analysing genomic data from soft tissue sarcoma from patients treated through the East Midland Sarcoma Service. In 2019, he commenced a post-doctoral fellowship in Bioinformatics with Prof. Deborah Mackay in the Faculty of Medicine at the University of Southampton.


FHEA, Academic Practice, University of Southampton 2020

PhD in Genetics and Genomic Biology, University of Leicester 2019

MSc, Clinical Immunology, University of Babylon 2011

BSc, Biological Sciences, University of Babylon 2007

Career History

Research Fellow: Analysing genomic data from 100,000 Genomes Project, identifying different kinds of genetic changes underpinning rare diseases, and developing analytical methods (2019-present)

Bioinformatics Intern: analysing whole exome sequence (WES) data from soft tissue sarcoma from patients (2018-2019)

Research interests

His research focuses on:

Rare Disease: His current research focuses on analysing genomic and clinical datasets from the 100,000 Genomes Project to identify potential novel genetic causes of growth disorders.

Developing Computational Methods: He developed an R-based tool (countToFPKM) for accurate quantification of gene expression (FPKM) from RNA-Seq data. He is currently implementing machine learning algorithms in informatic tools to improving identification of genomic anomalies (regions of homozygosity) in whole-genome sequence data.

Research group

Human Development and Health

Affiliate research group

Wessex Imprinting Group

PhD Supervision

Dr Alhendi has informally contributed to the supervision of one PhD student.

MSc Supervision:

Dr Alhendi currently supervises one MSc student.

MSc, The analysis of sequencing data from Beckwith-Wiedemann syndrome patients in 100,000 Genomes project. supervised by Dr Alhendi and Dr Wheway.

National and International responsibilities

Member Genomics England Clinical Interpretation Partnership (GeCIP)

Full member of Genetic Society - UK

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Lecturing, supervising, marking for the MSc in Genomic Medicine.

Dr Ahmed Alhendi
Faculty of Medicine, Room AB215, Mailpoint 801, South Academic Block, University Hospital Southampton, Tremona Road, Southampton, SO16 6YD

Room Number : SGH/Duthie/MP808

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